Results 41 to 50 of about 1,596,446 (317)

Biological handbook for engineers [PDF]

open access: yes, 1970
Microbiological background information is compiled in handbook for engineers and scientists working on bio-related projects. It is intended as aid in - /1/ evaluating effects of engineering procedures on microbial life, /2/ determining effects of ...

core   +1 more source

Stiffness of clays and silts: Modeling considerations [PDF]

open access: yes, 2014
A large database has recently been published that details the development of new empirical expressions for the stiffness reduction with strain of clays and silts.
Bolton, Malcolm, Vardanega, Paul J
core   +2 more sources

Engineering allostery [PDF]

open access: yesTrends in Genetics, 2014
Allosteric proteins have great potential in synthetic biology, but our limited understanding of the molecular underpinnings of allostery has hindered the development of designer molecules, including transcription factors with new DNA-binding or ligand-binding specificities that respond appropriately to inducers.
Raman, Srivatsan   +4 more
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Experiences and issues for environmental engineering sensor network deployments [PDF]

open access: yes, 2012
Sensor network research is a large and growing area of academic effort, examining technological and deployment issues in the area of environmental monitoring. These technologies are used by environmental engineers and scientists to monitor a multiplicity
Anda, M, Goodfield, D, Lee, K, Murray, D
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Let’s do Engineering broadens young children’s understanding of engineers

open access: yesFrontiers in Education
This study developed and applied a new job card methodology to investigate what 5-year-old children in Scotland understand in relation to engineers and engineering.
Helen Bridle, Gnanathusharan Rajendran
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Engineering Work in the Late Soviet Period: Routine, Creativity, and Project Discipline

open access: yesСоциология власти
This paper focuses on the labor practices of Soviet engineers in the period between the 1960s through the 1980s, with an emphasis on problems, challenges, and tensions arising in their everyday work.
Roman Abramov
doaj   +1 more source

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