Results 81 to 90 of about 1,590,550 (317)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Determination of level of physical preparedness of future engineers of railway transport. [PDF]

open access: yesPedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2012
Directions of increase of level of physical preparedness of student young people are considered. 48 students took part in research. The level of physical preparedness of students on the indexes of speeding up, co-ordination, flexibility and force was ...
Yefremova A.Y.
doaj  

Turning engineers into reflective university teachers [PDF]

open access: yes, 2006
Increasing attention to quality and innovation in Higher Education (HE) is enhancing the pedagogic knowledge of faculty members and thereby encouraging the academic success of their students.
Huet, I., Tavares, J., Weir, G.R.S.
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

University Engineering Faculty Depend on Scholarly Journals, Web Resources, and Face-to-Face Consultations to Help Them with Research. A Review of: Engel, D., Robbins, S., & Kulp, C. (2011). The information-seeking habits of engineering faculty. College & Research Libraries, 72(6), 548-567.

open access: yesEvidence Based Library and Information Practice, 2012
Objective – To study the information-seekingbehaviour of engineering faculty.Design – Online survey; Purposive sample.Setting – Engineering departments of 20 largepublic universities in various regions of theUnited States.Subjects – 903 engineering ...
Laura Newton Miller
doaj  

ERASE FROM THE PERSON OF THE GROUND OF PESTS AND SPIES": THE NORTH CAUCASIAN CHARACTERISTICS PROCESSES OF "BIG TERROR"

open access: yesГуманитарные и юридические исследования, 2021
The article is devoted to one of the most tragic periods in the history of our country - "great terror". The "harmful" processes of the 1930s in the North Caucasus are analyzed on the basis of their reflection in the regional press in 1937.
Elena Strekalova
doaj  

Pouvoirs urbains et ingénieurs de l’État

open access: yesMétropoles, 2007
The paper deals with the conception and realization of road building plans as a lens to understand changes in local decision-making and the relations between municipalities and the state. My purpose is to go beyond the usual studies of road constructions
Sébastien Gardon
doaj   +1 more source

Design hazard identification and the link to site experience [PDF]

open access: yes, 2017
The training, development and routes to charteredship of building design engineers have undergone a major transformation in recent years. Additionally, the duration and quality of site experience being gained by designers is reducing.
ASCE (American Society of Civil Engineers)   +13 more
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

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