Results 151 to 160 of about 1,465,240 (307)

Ce que cyber-parler veut dire: quels cadres théoriques pour l'analyse des conversations multimodales en réseau?

open access: yes, 2008
This is a methodological chapter in which the question for investigation is how to describe the effects of technological mediation on learning. The chapter focuses on the use of language by learners enrolled on a course of English-for-specific purposes ...
Lamy, Marie-Noëlle
core  

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

Tumor‐Derived Exosomes Deliver Membrane‐Bound Fgl2 to Activate FcγRIIB‐Mediated Immunosuppression in Myeloid‐Derived Suppressor Cells

open access: yesAdvanced Science, EarlyView.
This study reveals that the Fgl2‐FcγRIIB signaling axis is a key mechanism by which MDSCs mediate tumor immune evasion. Tumor‐derived exosomes systemically activate MDSCs via this pathway, positioning this axis as a promising broad‐spectrum target for cancer immunotherapy.
Fenglin Lin   +12 more
wiley   +1 more source

Lattice Genome Framework for Regionally Tailored Component‐Level Multi‐Objective Design in Additive Manufacturing

open access: yesAdvanced Science, EarlyView.
A Lattice Genome framework links geometric and process “genes” to lattice “phenotypes” via correction‐calibrated high‐throughput simulations and a growing performance database. Genome‐driven retrieval and recombination of unit cells enables component‐level, regionally tailored multi‐objective design: stress fields are programmed under constant relative
Haoyuan Deng   +8 more
wiley   +1 more source

Advanced Corneal Hydrogels: From Passive Replacement to Active Regeneration and Intelligent Interaction

open access: yesAdvanced Science, EarlyView.
This review charts the evolution of corneal hydrogels from passive replacements to active and intelligent systems, evaluating natural and synthetic materials while addressing design challenges such as transparency and strength. Advanced applications such as scarless wound healing, three‐dimensional bioprinting, and smart wearables are highlighted to ...
Xinwei Wang   +9 more
wiley   +1 more source

Cue-weighting in processing of prosodic boundaries in Dutch: An event-related potential (ERP) study. [PDF]

open access: yesPsychon Bull Rev
Geutjes J   +4 more
europepmc   +1 more source

Hacia una caracterización del Inglés para Fines Específicos (Turismo) [PDF]

open access: yes
Nowadays nobody doubts the importance of English as the lingua franca used in international communication. In addition to the numerous countries where English is the mother tongue, it is also spoken as a second language in other countries belonging to ...
Varela Méndez, Raquel
core   +1 more source

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