Results 81 to 90 of about 10,087,447 (327)

Disordered Environments in Spatial Games

open access: yes, 2001
The Prisoner's dilemma is the main game theoretical framework in which the onset and maintainance of cooperation in biological populations is studied. In the spatial version of the model, we study the robustness of cooperation in heterogeneous ecosystems
A. J. Bray   +37 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Institute of Enhanced Cooperation in European Union Law: Evolution of Legal Regulation

open access: yesМосковский журнал международного права
INTRODUCTION. The article presents the evolution of legal regulation of the institution of enhanced cooperation as a legal form of flexible integration in European Union (EU) law. Flexible integration is a fairly widespread and objectively existing legal
V. V. Voinikov, R. R. Amiraslanov
doaj   +1 more source

Separating conditional and unconditional cooperation in a sequential Prisoner's Dilemma game. [PDF]

open access: yesPLoS ONE, 2017
Most theories of social exchange distinguish between two different types of cooperation, depending on whether or not cooperation occurs conditional upon the partner's previous behaviors.
Raoul Bell, Laura Mieth, Axel Buchner
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Evolutionary Games defined at the Network Mesoscale: The Public Goods game

open access: yes, 2010
The evolutionary dynamics of the Public Goods game addresses the emergence of cooperation within groups of individuals. However, the Public Goods game on large populations of interconnected individuals has been usually modeled without any knowledge about
Criado, R.   +4 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Enhanced Cooperation in an Asymmetric Model of Tax Competition [PDF]

open access: yes
This paper analyzes enhanced cooperation agreements in corporate taxation in a three country tax competition model where countries differ in size. We characterize equilibrium tax rates and the optimal tax responses due to the formation of an enhanced ...
Hendrik Vrijburg, Ruud A. De Mooij
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Implications for the U.S. of Anglo-French Defense Cooperation [PDF]

open access: yes, 2012
The paper analyzes, from a predominantly UK perspective, the implications for the U.S. of the November 2, 2010, Anglo-French Defence Cooperation Treaty.
Antill, Peter D.   +4 more
core   +2 more sources

Home - About - Disclaimer - Privacy