Results 71 to 80 of about 839,114 (299)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Adaptace českého právního řádu na zřízení Úřadu evropského veřejného žalobce

Acta Universitatis Carolinae Iuridica, 2019
Council Regulation (EU) 2017/1939 of 12 October 2017 implementing enhanced cooperation on the establishment of the European Public Prosecutor’s Office (“the EPPO”) was published in the Official Journal of the European Union on 31 October 2017.
Jiří Pavlík
doaj   +1 more source

Enhanced Cooperation in Corporate Taxation [PDF]

, 2011
In this thesis I study the harmful competition between national governments to attract multinational companies into their country, by designing a competitive corporate tax system.
Vrijburg, H. (Hendrik)
core   +2 more sources

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

The Institute of Enhanced Cooperation in European Union Law: Evolution of Legal Regulation

Московский журнал международного права
INTRODUCTION. The article presents the evolution of legal regulation of the institution of enhanced cooperation as a legal form of flexible integration in European Union (EU) law. Flexible integration is a fairly widespread and objectively existing legal
V. V. Voinikov, R. R. Amiraslanov
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Multistakeholder governance processes as production sites: enhanced cooperation "in the making"

Internet Policy Review, 2016
The paper combines actor-network theory and interpretative policy analysis to conceptualise multistakeholder arrangements in internet governance as production sites in which heterogeneous actors engage in dynamic processes of social ordering such as ...
Julia Pohle
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Optimal interdependence between networks for the evolution of cooperation [PDF]

, 2013
Recent research has identified interactions between networks as crucial for the outcome of evolutionary games taking place on them. While the consensus is that interdependence does promote cooperation by means of organizational complexity and enhanced ...
A Halu, A Szolnoki, A Szolnoki, A Szolnoki, A Szolnoki, BJ Kim, C Gracia-Lázaro, C Gracia-Lázaro, C Hauert, CM Schneider, CP Roca, D Zhou, F Fu, F Fu, F Pinheiro, FC Santos, FC Santos, FC Santos, FC Santos, FC Santos, G Abramson, G Li, G Szabó, G Szabó, GI Simko, GJ Baxter, H Ebel, HW Lau, IG Portillo, J Gao, J Gómez-Gardeñes, J Gómez-Gardeñes, J Gómez-Gardeñes, J Gómez-Gardeñes, J Peña, J Poncela, J Poncela, J Poncela, J Tanimoto, J Tanimoto, JM Pacheco, KH Schlag, LE Blume, M Brede, M Brede, M Perc, M Perc, M Tomassini, M Tomassini, MA Nowak, MA Nowak, MG Zimmermann, MN Kuperman, N Masuda, N Masuda, P Csermely, R Dickman, R Parshani, R-H Li, S Assenza, S Gómez, S Havlin, S Lee, S-W Son, SV Buldyrev, TP Peixoto, X Huang, Y Wang, Z Rong, Z Wang, Z Wang, Z Wang, Z Wang   +72 more
core   +3 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source