Results 61 to 70 of about 839,114 (299)
Book Review: Michael Baun and Dan Marek (eds.) The New Member States and the European Union. Foreign Policy and Europeanization [PDF]
Romanian Journal of European Affairs, 2014 A radical decision at the time, the 2004 enlargement constituted a critical juncture for the Central and Eastern European Countries. Although a great deal of literature has been written in regard to other aspects of Europeanization, the effects of EU ...
Adelin Dumitru
doaj
Determinants of public cooperation in multiplex networks
New Journal of Physics, 2017 Synergies between evolutionary game theory and statistical physics have significantly improved our understanding of public cooperation in structured populations.
Federico Battiston +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Bottom-Up Approaches to Synthetic Cooperation in Microbial Communities
Life, 2019 Microbial cooperation pervades ecological scales, from single-species populations to host-associated microbiomes. Understanding the mechanisms promoting the stability of cooperation against potential threats by cheaters is a major question that only ...
Daniel Rodríguez Amor +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Journal of Microbiology, Immunology and Infection, 2017 Background: Over time, as newly emerging infectious diseases have become increasingly common and more easily spread, it has become clear that traditional response mechanisms have proven inadequate to the task of prevention and control.
Jonathan Schwartz, Muh-Yong Yen
doaj +1 more source
Fixation probabilities for any configuration of two strategies on regular graphs
, 2016 Population structure and spatial heterogeneity are integral components of evolutionary dynamics, in general, and of evolution of cooperation, in particular. Structure can promote the emergence of cooperation in some populations and suppress it in others.
Chen, Yu-Ting +2 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source