Results 61 to 70 of about 3,055,415 (293)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Enhanced Cooperation in an Asymmetric Model of Tax Competition [PDF]

open access: yes
This paper analyzes enhanced cooperation agreements in corporate taxation in a three country tax competition model where countries differ in size. We characterize equilibrium tax rates and the optimal tax responses due to the formation of an enhanced ...
Ruud A. De Mooij, Hendrik Vrijburg
core   +1 more source

Determinants of public cooperation in multiplex networks

open access: yesNew Journal of Physics, 2017
Synergies between evolutionary game theory and statistical physics have significantly improved our understanding of public cooperation in structured populations.
Federico Battiston   +2 more
doaj   +1 more source

Prospects for India-Serbia collaboration within the BRICS framework [PDF]

open access: yesSrpska Politička Misao
This scholarly paper examines the prospects and strategic significance of cooperation between Serbia and India within the BRICS platform. Special attention is devoted to the economic dimension of cooperation, especially in international politics ...
Terzić Predrag, Anchev Stefan
doaj   +1 more source

Enhanced Chelate Cooperativity in Polar Solvents

open access: yesJournal of the American Chemical Society, 2017
High-throughput UV-vis titrations in combination with chemical double-mutant cycles (DMCs) have been used to study the competition of a polar solvent for formation of intramolecular H-bonds. Twenty-four different zinc porphyrin-pyridine complexes were investigated in mixtures of toluene and phenol.
Stefan Henkel   +4 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Impact of interaction style and degree on the evolution of cooperation on Barabási-Albert scale-free network. [PDF]

open access: yesPLoS ONE, 2017
In this work, we study an evolutionary prisoner's dilemma game (PDG) on Barabási-Albert scale-free networks with limited player interactions, and explore the effect of interaction style and degree on cooperation.
Fengjie Xie, Jing Shi, Jun Lin
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Bottom-Up Approaches to Synthetic Cooperation in Microbial Communities

open access: yesLife, 2019
Microbial cooperation pervades ecological scales, from single-species populations to host-associated microbiomes. Understanding the mechanisms promoting the stability of cooperation against potential threats by cheaters is a major question that only ...
Daniel Rodríguez Amor   +1 more
doaj   +1 more source

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