Results 51 to 60 of about 839,114 (299)

Direct reciprocity in spatial populations enhances R-reciprocity as well as ST-reciprocity. [PDF]

PLoS ONE, 2013
As is well-known, spatial reciprocity plays an important role in facilitating the emergence of cooperative traits, and the effect of direct reciprocity is also obvious for explaining the cooperation dynamics.
Kohei Miyaji, Jun Tanimoto, Zhen Wang, Aya Hagishima, Naoki Ikegaya   +4 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Cooperation of Oligodeoxynucleotides and Synthetic Molecules as Enhanced Immune Modulators

Frontiers in Nutrition, 2019
Unmethylated cytosine–guanine dinucleotide (CpG) motifs are potent stimulators of the host immune response. Cellular recognition of CpG motifs occurs via Toll-like receptor 9 (TLR9), which normally activates immune responses to pathogen-associated ...
Shireen Nigar, Takeshi Shimosato
doaj   +1 more source

Impact of interaction style and degree on the evolution of cooperation on Barabási-Albert scale-free network. [PDF]

PLoS ONE, 2017
In this work, we study an evolutionary prisoner's dilemma game (PDG) on Barabási-Albert scale-free networks with limited player interactions, and explore the effect of interaction style and degree on cooperation.
Fengjie Xie, Jing Shi, Jun Lin
doaj   +1 more source

Evolutionary Games defined at the Network Mesoscale: The Public Goods game

, 2010
The evolutionary dynamics of the Public Goods game addresses the emergence of cooperation within groups of individuals. However, the Public Goods game on large populations of interconnected individuals has been usually modeled without any knowledge about
Criado, R., Gómez-Gardeñes, J., Romance, M., Sánchez, A., Vilone, D.   +4 more
core   +1 more source

Evolution of Cooperation among Mobile Agents [PDF]

, 2011
We study the effects of mobility on the evolution of cooperation among mobile players, which imitate collective motion of biological flocks and interact with neighbors within a prescribed radius $R$. Adopting the prisoner's dilemma game and the snowdrift
Aktipis, Brockmann, Cardillo, Chen, Chen, Chen, Chen, Dai, Doebeli, Dossetti, Du, Fu, González, González, Guan, Gómez-Gardeñes, Hauert, Helbing, Jiang, Jianxi Gao, Kleinberg, Meloni, Moyano, Nagy, Nowak, Nowak, Olfati-Saber, Perc, Perc, Perc, Perc, Peña, Poncela, Poncela, Ren, Santos, Santos, Santos, Sicardi, Song, Szabó, Szabó, Szabó, Szolnoki, Szolnoki, Szolnoki, Szolnoki, Szolnoki, Szolnoki, Tang, Vainstein, Van Segbroeck, Vicsek, Wu, Xiaoming Xu, Yang, Yunze Cai, Zhuo Chen, Zimmermann   +58 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Enhanced Chelate Cooperativity in Polar Solvents

Journal of the American Chemical Society, 2017
High-throughput UV-vis titrations in combination with chemical double-mutant cycles (DMCs) have been used to study the competition of a polar solvent for formation of intramolecular H-bonds. Twenty-four different zinc porphyrin-pyridine complexes were investigated in mixtures of toluene and phenol.
Stefan Henkel, Maria Cristina Misuraca, Yudi Ding, Maxime Guitet, Christopher A. Hunter   +4 more
openaire   +2 more sources

Cooperation enhanced by inhomogeneous activity of teaching for evolutionary Prisoner's Dilemma games

, 2006
Evolutionary Prisoner's Dilemma games with quenched inhomogeneities in the spatial dynamical rules are considered. The players following one of the two pure strategies (cooperation or defection) are distributed on a two-dimensional lattice.
A Szolnoki, Cressman R., G Szabó, Gintis H., Marro J., Perc M., Perc M., Perc M., Szabó G., Vainstein M. H. Silva A. T. C. Arenzon J. J., Weibull J. W., Wu Z.-X.   +11 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source