Results 51 to 60 of about 3,055,415 (293)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The effect of geographical proximity on scientific cooperation among Chinese cities from 1990 to 2010. [PDF]
PLoS ONE, 2014 The relations between geographical proximity and spatial distance constitute a popular topic of concern. Thus, how geographical proximity affects scientific cooperation, and whether geographically proximate scientific cooperation activities in fact ...
Haitao Ma +3 more
doaj +1 more source
Using cooperative learning to enhance critical reflection [PDF]
2014 IEEE Frontiers in Education Conference (FIE) Proceedings, 2014 Over the past two decades, one of the key changes in Engineering curricula has been in the emphasis placed on the development of personal transferable skills. Employers also profess to seek these competencies when making recruiting decisions. Such skills include the ability to learn through collaboration and through meaningful critical reflection on ...
Meriel Huggard +2 more
openaire +3 more sources
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Cooperation of Oligodeoxynucleotides and Synthetic Molecules as Enhanced Immune Modulators
Frontiers in Nutrition, 2019 Unmethylated cytosine–guanine dinucleotide (CpG) motifs are potent stimulators of the host immune response. Cellular recognition of CpG motifs occurs via Toll-like receptor 9 (TLR9), which normally activates immune responses to pathogen-associated ...
Shireen Nigar, Takeshi Shimosato
doaj +1 more source
HOW CAN SOCIAL HERDING ENHANCE COOPERATION? [PDF]
Advances in Complex Systems, 2013 We study a system in which N agents have to decide between two strategies θi(i ∈ 1 … N), for defection or cooperation, when interacting with other n agents (either spatial neighbors or randomly chosen ones). After each round, they update their strategy responding nonlinearly to two different information sources: (i) the payoff ai(θi, fi) received from
Frank Schweitzer +2 more
openaire +5 more sources
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Book Review: Michael Baun and Dan Marek (eds.) The New Member States and the European Union. Foreign Policy and Europeanization [PDF]
Romanian Journal of European Affairs, 2014 A radical decision at the time, the 2004 enlargement constituted a critical juncture for the Central and Eastern European Countries. Although a great deal of literature has been written in regard to other aspects of Europeanization, the effects of EU ...
Adelin Dumitru
doaj
Direct reciprocity in spatial populations enhances R-reciprocity as well as ST-reciprocity. [PDF]
PLoS ONE, 2013 As is well-known, spatial reciprocity plays an important role in facilitating the emergence of cooperative traits, and the effect of direct reciprocity is also obvious for explaining the cooperation dynamics.
Kohei Miyaji +4 more
doaj +1 more source
Cooperativity in the Enhanced Piezoelectric Response of Polymer Nanowires [PDF]
Advanced Materials, 2014 Multilayered, aligned arrays of organic nanowires show unique advantages in their piezoelectric response. Here, the cooperative, electromechanical mechanism at the base of the enhanced response of aligned arrays of piezoelectric nanostructures in mutual contact is unveiled. An enhancement of the piezoelectric voltage by two orders of magnitude compared
L. Persano +4 more
openaire +6 more sources