Results 211 to 220 of about 761,191 (268)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Metabolic support of trained immune responses in myeloid cells. [PDF]

Elife
Jarit-Cabanillas A, Dunphy G, Virga F, Van den Bossche J, Sancho D.   +4 more
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Correction to: Proteomic and metabolomic analysis of platelet related samples reveals energy metabolism disorders in hepatocellular carcinoma. [PDF]

J Transl Med
Ruan X, Hu Z, Shen F, Chen Y, Zhong Z, Ou G, Luo X, Qin X, Wang H.   +8 more
europepmc   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source

Inducing Ferroptosis to Enhance Radiotherapy in Head and Neck Cancer: Mechanisms, Radiosensitization Strategies, and Normal Tissue Considerations. [PDF]

Cells
Lee J, Roh JL.
europepmc   +1 more source

Metabolomics reveal drought-stress responses in guayule, a semi-arid rubber crop. [PDF]

Metabolomics
Phan H, Abdel-Haleem H.
europepmc   +1 more source

Integrative Transcriptomic and Metabolomic Analyses Provide Insights into the Regulatory Basis of <i>Streptomyces pactum</i> Act12-Associated Root Development in Wheat. [PDF]

Plants (Basel)
Zhang J, Wen H, Wang Y, Wang Z, Zheng X, Shan H, Yang B.   +6 more
europepmc   +1 more source

No-tillage with straw mulching enhances grain yield and water use efficiency of wheat by enhancing sugar metabolism in flag leaves and grains in rainfed Loess Plateau, China. [PDF]

Front Plant Sci
Wu H, Li L, Mumtaz MZ, Meng H, Zhang Y, Khan KS, Zhu Z, Tian X, Wang L, Xu J.   +9 more
europepmc   +1 more source