Results 221 to 230 of about 761,191 (268)

Endonuclease G restores lipid homeostasis in spontaneously hypertensive rats: implications for mitochondrial function. [PDF]

Front Physiol
Mlejnek P, Šimáková M, Šilhavý J, Liška F, Mráček T, Houštěk J, Marková I, Hüttl M, Malínská H, Pravenec M.   +9 more
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The consequences of enhanced cell-autonomous glucose metabolism

Trends in Endocrinology and Metabolism, 2012
The intake and metabolism of carbohydrates for the generation of energy and biomass is evolutionarily conserved, down to the most primitive of cells. Although a basal rate of glucose metabolism occurs in all cells, the processing rates of glucose can become dramatically enhanced when cells acquire malignant properties, or remain undifferentiated.
Jason W Locasale
exaly   +3 more sources

Metabolic and DNA checkpoints for the enhancement of Al tolerance

Journal of Hazardous Materials, 2022
Acidic soils are a major limiting factor for food production in many developing countries. High concentrations of soluble Al cations, particularly Al3+, inhibit cell division and root elongation in plants. Al3+ damages several biomolecules, including DNA, impairing gene expression and cell cycle progression. Notably, the loss-of-function mutants of DNA
João Antonio, Siqueira, Marcelle Ferreira, Silva, Thiago, Wakin, Adriano, Nunes-Nesi, Wagner L, Araújo   +4 more
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Enhancement of metabolism of jeopardized myocardium by nifedipine

International Journal of Cardiology, 1987
To define effects of nifedipine on regional metabolism in jeopardized myocardium we quantified accumulation of carbon-11 labeled palmitate ([11C]palmitate) in patients with acute myocardial infarction by positron emission tomography in a randomized, double-blind, placebo controlled study. Tomographic studies were performed prior to treatment as soon as
A S, Jaffe, D R, Biello, B E, Sobel, E M, Geltman   +3 more
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Enhancement of the metabolism and hepatotoxicity of trichloroethylene and perchloroethylene

Biochemical Pharmacology, 1977
Abstract Trichloroethylene anesthesia (1% for 2 hr) caused acute hepatic injury in rats pretreated with five different inducers of the hepatic mixed function oxidase system, phenobarbital, Aroclor 1254, hexachlorobenzene, 3-methylcholanthrene and pregnenolone-16-α-carbonitrile.
M T, Moslen, E S, Reynolds, S, Szabo
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In vitro enhancement of aniline metabolism by paraoxon

Toxicology and Applied Pharmacology, 1972
Paraoxon in concentrations from 2 × 10−5 m to 1 × 10−3 m enhanced the in vitro microsomal metabolism of aniline in livers obtained from rats, mice, rabbits, dogs and man. Paraoxon is several thousand times more potent as an enhancing agent than acetone. Enhancement of drug metabolism by acetone is inhibited by SKF 525A, but enhancement of metabolism by
J T, Stevens, J J, McPhillips, R E, Stitzel   +2 more
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Metabolic engineering for enhanced oil in biomass

Progress in Lipid Research, 2019
The world is hungry for energy. Plant oils in the form of triacylglycerol (TAG) are one of the most reduced storage forms of carbon found in nature and hence represent an excellent source of energy. The myriad of applications for plant oils range across foods, feeds, biofuels, and chemical feedstocks as a unique substitute for petroleum derivatives ...
Vanhercke, Thomas, Dyer, John M., Mullen, Robert T., Kilaru, Aruna, Rahman, Mahbubur, Petrie, James R., Green, Allan G., Yurchenko, Olga, Singh, Surinder P.   +8 more
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Strategies to Enhance Metabolic Stabilities

2019
Macrocyclic peptides are a unique class of molecules that display a relatively constrained peptidic backbone as compared to their linear counterparts leading to the defined 3-D orientation of the constituent amino acids (pharmacophore). Although they are attractive candidates for lead discovery owing to the unique conformational features, their ...
Khatri, Bhavesh, Nuthakki, Venkateswara Rao, Chatterjee, Jayanta   +2 more
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Overview of Metabolism and Bioavailability Enhancement of Polyphenols

Journal of Agricultural and Food Chemistry, 2013
A proper diet is one of major factors contributing to good health and is directly related to general condition of the organism. Phenolic compounds are abundant in foods and beverages (fresh and processed fruits and vegetables, leguminous plants, cereals, herbs, spices, tea, coffee, wine, beer) and their pleiotropic biological activities result in ...
Urszula, Lewandowska, Karolina, Szewczyk, Elżbieta, Hrabec, Anna, Janecka, Sylwia, Gorlach   +4 more
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