Results 241 to 250 of about 761,191 (268)
Some of the next articles are maybe not open access.
Enhancing cocaine metabolism with butyrylcholinesterase as a treatment strategy
Drug and Alcohol Dependence, 1997Existing pharmacodynamic approaches to cocaine abuse treatment have not been widely successful. An alternative, pharmacokinetic, approach is to enhance cocaine metabolism by administration of butyrylcholinesterase (BChE), a major cocaine-metabolizing enzyme in primates.
openaire +2 more sources
Nanotechnology Reprogramming Metabolism for Enhanced Tumor Immunotherapy
ACS NanoMutation burden, hypoxia, and immunoediting contribute to altered metabolic profiles in tumor cells, resulting in a tumor microenvironment (TME) characterized by accumulation of toxic metabolites and depletion of various nutrients, which significantly hinder the antitumor immunity via multiple mechanisms, hindering the efficacy of tumor immunotherapies.
Yangkai Zhou +4 more
openaire +2 more sources
Enhancement of Hypoxic Pulmonary Vasoconstriction by Metabolic Acidosis in Dogs
Anesthesiology, 1990The effects of HCl infusion on multipoint mean pulmonary arterial pressure (PAP)/cardiac index (CI) plots in pentobarbital-anesthetized dogs whose lungs were ventilated alternately in hyperoxia (fraction of inspired O2 [FIO2], 0.4) and hypoxia (FIO2, 0.1) were investigated.
Lejeune, Philippe +5 more
openaire +3 more sources
Targeting lipid metabolism to enhance cancer immunotherapy
Biochimica et Biophysica Acta (BBA) - Reviews on CancerIn recent years, the interaction between lipid metabolism and immune checkpoint inhibitors (ICIs) has become a key area of research in cancer treatment. Tumor cells utilize lipid metabolism reprogramming to promote rapid proliferation, evade immune surveillance, and develop resistance to treatment, highlighting the significant role of lipid metabolism ...
Dan, Zhao, Lei, Wu, Yongsheng, Li
openaire +2 more sources
Nutrition to Enhance Metabolic-Bariatric Surgery Outcomes
Obesity SurgeryGender-specific post-surgical goals for 12-month percent body fat (%BF) based on World Health Organization (WHO) obesity thresholds and for lean mass-sparing were published as preliminary body composition (BC) guidelines to address a knowledge gap in metabolic-bariatric surgery (MBS).
openaire +2 more sources
An enhancement of liver mitochondrial metabolism
Gastroenterologia Japonica, 1973Hidenari Takasan, Kazue Ozawa
openaire +1 more source