Results 231 to 240 of about 761,191 (268)
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Enhancement and Inhibition of Drug Metabolism
Annual Review of Pharmacology, 1971A large number of factors can alter rates of drug metabolism. This re view wiII discuss the enhancement and inhibition of drug metabolism. By enhancement is meant that increase in rate of in vitro drug metabolism ob served following the inclusion of other drugs or chemicals in the reaction mixture.
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Enhancement of renal and hepatic glutathione metabolism by dimethylthiourea
Toxicology Letters, 1993Dimethylthiourea (DMTU), a free radical scavenger, was administered to rats to study its effect on renal and hepatic glutathione metabolism, since it is a potential sulfhydryl donor. Six hours following DMTU, renal GSH content was significantly (P < 0.05) increased (10%), and was increased further after 24 h (28%) (P < 0.001).
L S, Milner, S H, Wei, M T, Houser
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Enhanced precision and efficiency in metabolic regulation: Compartmentalized metabolic engineering
Bioresource TechnologyMetabolic engineering has witnessed remarkable advancements, enabling successful large-scale, cost-effective and efficient production of numerous compounds. However, the predominant expression of heterologous genes in the cytoplasm poses limitations, such as low substrate concentration, metabolic competition and product toxicity.
Rubing Wang +5 more
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Metabolic Enhancement of the Soldier Brain
2019Abstract This chapter highlights current understanding of human limits of performance, with emphasis on soldier-related research and the mechanisms of stress that typically affect soldier performance. How we exercise, eat, rest, and manage our emotions has a major effect on brain metabolism and human performance.
Karl E. Friedl, Stephen J. Grate
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Metabolic engineering for enhanced hydrogen production: a review
Canadian Journal of Microbiology, 2013Hydrogen gas exhibits potential as a sustainable fuel for the future. Therefore, many attempts have been made with the aim of producing high yields of hydrogen gas through renewable biological routes. Engineering of strains to enhance the production of hydrogen gas has been an active area of research for the past 2 decades.
Yogesh, Goyal +2 more
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Enhancement of lipid accumulation in microalgae by metabolic engineering
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2019Microalgal lipids have drawn great attention as a promising sustainable resource for biodiesel or food supplement production. The development of high-performance strains of microalgae by metabolic engineering is invaluable for increasing the quantity or quality of desired lipids.
Xiao-Man, Sun +4 more
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Enhancing the treatment of metabolic syndrome with integrative medicine
Journal of Integrative Medicine, 2013Metabolic syndrome, with the main clinical manifestations of obesity, dyslipidemia, elevated blood pressure, and elevated blood glucose levels, has become an increasingly prevalant global public health concern. Metabolic syndrome is a convergence of multiple risk factors related to cardiovascular disease.
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Enhanced thyroxine metabolism in hexachlorobenzene-intoxicated rats
Journal of Endocrinological Investigation, 1989The effect of hexachlorobenzene (HCB) (1 g/kg bw) administration for 4 weeks, on thyroxine (T4) and triiodothyronine (T3) metabolism was studied in Wistar rats. The effect on serum binding of T4 has also been studied. Animals were injected with a tracer dose of either labeled hormone and by examining serum L-125I-T4 and L-125-I-T3, kinetics of ...
D L, Kleiman de Pisarev +2 more
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Isopropanol enhancement of carbon tetrachloride metabolism in vivo
Life Sciences, 1982We examined the effects of isopropanol (ISOP) pretreatment on the metabolism of 14CCl4 to 14CO2 and CHCl3 exhaled in the breath, to 14C metabolite excreted in 24 hr urine and feces from 0 to 24 hr, and to 14C metabolite bound to liver at 24 hr. Fasted male rats were given 0.1 or 2.0 mmoles 14CCl4/kg.
E S, Reynolds, M T, Moslen, R J, Treinen
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The Enhanced Effect of Atenolol on Hypertension in Metabolic Syndrome
Metabolic Syndrome and Related Disorders, 2011In metabolic syndrome, hypertension has been noted as one of the most important risk factors that contributes to cardiovascular disease. We have evaluated the effect of a selective adrenergic β(1)-receptor blocker, atenolol, on blood pressure and pulse rate in metabolic syndrome.Metabolic syndrome patients with hypertension (n=28) and a control group ...
Naohiko, Ueno, Yoshiko, Satou
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