Results 181 to 190 of about 668,045 (318)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Gel-confined strain amplifies FRET efficiency toward red emission enhancement beyond pressure quenching. [PDF]

open access: yesSci Adv
Yu X   +11 more
europepmc   +1 more source

Enhanced captured material

open access: yes
D2.2 will deliver the enhanced captured footage to S&M for them to again evaluate and use in their improved HDR shot pipeline.
openaire   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Reconfigurable second-harmonic generation via plasmonic nanoslits counteracting strain-induced suppression in monolayer MoS<sub>2</sub>. [PDF]

open access: yesSci Adv
Sharma S   +10 more
europepmc   +1 more source

Enhanced Material Estimation with Multi-Spectral CT

open access: yesElectronic Imaging, 2021
Sandamali Devadithya, David Castañón
openaire   +1 more source

Application of Biuret, Dicyandiamide, or Urea as a Cathode Buffer Layer toward the Efficiency Enhancement of Polymer Solar Cells

open access: yes, 2014
Three amino-containing small-molecule organic materials-biuret, dicyandiamide (DCDA), and urea were successfully applied as novel cathode buffer layers (CBLs) in P3HT:PCBM bulk heterojunction polymer solar cells (BHJ-PSCs) for the first time, resulting ...
Zhang, WF (Zhang, Wenfeng)   +7 more
core  

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