Results 61 to 70 of about 668,045 (318)

Fire-retardant effect of titania-polyurea coating and additional enhancement via aromatic diamine and modified melamine polyphosphate

open access: yes, 2022
Polymeric materials and composites are well suited to support structures in marine conditions due to their corrosion resistance. However, their low glass transition temperature makes them vulnerable to softening at high temperatures.
Wang, Haojing   +6 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Kinetics in Mg-based hydrogen storage materials: Enhancement and mechanism

open access: yesJournal of Magnesium and Alloys, 2019
Mg-based materials have been intensively studied for hydrogen storage applications due to their high energy density up to 2600 Wh/kg or 3700 Wh/L. However, the Mg-based materials with poor kinetics and the necessity for a high temperature to achieve 0.1 ...
Qun Luo   +5 more
doaj   +1 more source

Enhancement of optical absorption in Ga-chalcopirite-based intermediate-band materials for high efficiency solar cells

open access: yes, 2010
We present absorption properties enhancement for two CuGaS2-based intermediate-band materials, as promising compounds for high efficiency, lower-cost photovoltaic devices.
P. Wahnón   +5 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Lobetyolin reshapes gut microbiota and bile acid metabolism to improve androgen-driven PCOS phenotypes in mice

open access: yesFrontiers in Microbiology
AimTo clarify the molecular mechanisms through which lobetyolin (LT) modifies the gut microbiota-bile acid axis to multitarget the regulation of hyperandrogenism, insulin resistance, chronic low-grade inflammation, and endometrial dysfunction ...
Lijuan Li   +9 more
doaj   +1 more source

Source monitoring is not always enhanced for valenced material [PDF]

open access: yesMemory & Cognition, 2007
Source monitoring for valenced materials has received very little attention from researchers interested in the residual effects that emotion can have on memory. The three previous studies that examined memory for valenced material found a source-monitoring enhancement effect. By contrast, we used two different combinations of sources and found a novel,
Gabriel I, Cook   +2 more
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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