Results 71 to 80 of about 1,538,076 (299)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Metamaterial control of stimulated Brillouin scattering

open access: yes, 2016
Using full opto-acoustic numerical simulations, we demonstrate enhancement and suppression of the SBS gain in a metamaterial comprising a subwavelength cubic array of dielectric spheres suspended in a dielectric background material.
de Sterke, C. Martijn   +5 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Capacitance enhancement by ion-laminated borophene-like layered materials

open access: yesNature Communications
Atomically flat two-dimensional networks of boron are attracting attention as post-graphene materials. An introduction of cations between the boron atomic layers can exhibit unique electronic functions that are not achieved by neutral graphene or its ...
Tetsuya Kambe   +14 more
doaj   +1 more source

THE EFFECT OF MULTIMEDIA-BASED TEACHING MATERIALS IN SCIENCE TOWARD STUDENTS’ COGNITIVE IMPROVEMENT

open access: yesJurnal Pendidikan IPA Indonesia, 2016
This study is a meta-analysis study that aimed to determine the effect of multimedia-based teaching materials in science learning to students' cognitive enhancement.
Khoiriah Khoiriah   +2 more
doaj   +1 more source

Corpus-Based Materials and Learning Non-Congruent Idioms by Iranian EFL Learners: Enhanced and Unenhanced Input [PDF]

open access: yesJournal of Language Horizons, 2019
The current study aimed at probing the impact of using enhanced and unenhanced corpus-based material on non-congruent idiom learning by Iranian female intermediate EFL learners.
Hoda Estefaei, Alireza Amjadiparvar
doaj   +1 more source

Large enhancement of the thermoelectric power factor in disordered materials through resonant scattering

open access: yes, 2019
In the search for more efficient thermoelectric materials, scientists have placed high hopes in the possibility of enhancing the power factor using resonant states.
Adessi, Christophe   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

In-Depth Characterization of bZIP Genes in the Context of Endoplasmic Reticulum (ER) Stress in Brassica campestris ssp. chinensis

open access: yesPlants
Numerous studies have been conducted to investigate the genomic characterization of bZIP genes and their involvement in the cellular response to endoplasmic reticulum (ER) stress.
Aliya Ayaz   +6 more
doaj   +1 more source

Reflective Inverse Diffusion

open access: yesApplied Sciences, 2016
Phase front modulation was previously used to refocus light after transmission through scattering media. This process has been adapted here to work in reflection.
Kenneth Burgi   +3 more
doaj   +1 more source

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