Results 91 to 100 of about 668,045 (318)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Giant ZT enhancement in rhombohedral GeTe-based thermoelectric materials

Nature Communications
The peak figure of merit (ZT) of GeTe-based thermoelectric (TE) materials is typically attained in the high-temperature cubic phase, where the inevitable phase transition raises concerns over interfacial instability during operation.
Jincheng Yu, Xiaodong Liu, Yilin Jiang, Chen Chen, Jing-Wei Li, Haihua Hu, Lin Song, Tian Xie, Bin-Bin Ruan, Yu Pan, Guoyu Wang, B. Layla Mehdi, Xiaoyuan Zhou, Jing-Feng Li   +13 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Purcell enhancement of the parametric down-conversion in two-dimensional nonlinear materials

APL Photonics, 2019
Ultracompact nonlinear optical devices utilizing two-dimensional (2D) materials and nanostructures are emerging as important elements of photonic circuits.
Mikhail Tokman, Zhongqu Long, Sultan AlMutairi, Yongrui Wang, Valery Vdovin, Mikhail Belkin, Alexey Belyanin   +6 more
doaj   +1 more source

Generative detail enhancement for physically based materials

Proceedings of the Special Interest Group on Computer Graphics and Interactive Techniques Conference Conference Papers
We present a tool for enhancing the detail of physically based materials using an off-the-shelf diffusion model and inverse rendering. Our goal is to enhance the visual fidelity of materials with detail that is often tedious to author, by adding signs of wear, aging, weathering, etc. As these appearance details are often rooted in real-world processes,
Saeed Hadadan, Benedikt Bitterli, Tizian Zeltner, Jan Novák, Fabrice Rousselle, Jacob Munkberg, Jon Hasselgren, Bartlomiej Wronski, Matthias Zwicker   +8 more
openaire   +2 more sources

Active Enhancement of Slow Light Based on Plasmon-Induced Transparency with Gain Materials

, 2018
As a plasmonic analogue of electromagnetically induced transparency (EIT), plasmon-induced transparency (PIT) has drawn more attention due to its potential of realizing on-chip sensing, slow light and nonlinear effect enhancement.
Zhaojian Zhang, Jie Huang, Xin He, Yunxin Han, Siyu Xu, Jingjing Zhang, Dingbo Chen, Junbo Yang   +7 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Work-hardening and ductility enhancement mechanism of cold rolled multiphase TRIP steels

, 2018
The work hardening behavior of a high strength sheet steel has been studied in relation to the deformation induced martensitic transformation (DIMT) of retained austenite (gamma(R)).
Chang, YW, Chung, JH, Jeon, JB
core   +1 more source

Near field enhancements from angled surface defects : a comparison of scanning laser source and scanning laser detection techniques [PDF]

, 2011
Enhancement of the Rayleigh wave signal amplitude at a surface defect, due to interference of incident, reflected and mode converted waves, has been reported by several authors, and it has been suggested that this could be used as a fingerprint of the ...
Edwards, R. S. (Rachel S.), A. R. Clough, B. Dutton, Clough, A. R., Dutton, B. (Ben), R. S. Edwards   +5 more
core   +1 more source