Results 181 to 190 of about 8,934,200 (403)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

ENHANCED PASSIVE IMMUNITY TO STREPTOCOCCUS INFECTION IN RABBITS [PDF]

, 1930
Frédérick Gay, A. R. Clark
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Five novel cis-regulatory deletions of SOX10 cause Waardenburg syndrome type II

Frontiers in Audiology and Otology
IntroductionWaardenburg syndrome (WS) is a genetic disorder characterized by hearing loss, hypopigmentation, and distinct facial features. Despite > 60% molecular diagnosis rate for WS patients, pathogenic variants within coding regions are ...
Yu Huang, Yu Huang, Jia Geng, Jia Geng, Yang Long, Wenyu Xiong, Wenyu Xiong, Lu Kang, Lu Kang, Meilin Chen, Meilin Chen, Ting Tang, Ting Tang, Mingjun Zhong, Mingjun Zhong, Fengxiao Bu, Fengxiao Bu, Yu Lu, Yu Lu, Jing Cheng, Jing Cheng, Huijun Yuan, Huijun Yuan   +22 more
doaj   +1 more source

The Possibility of Enhanced Hg^202 as a Source of Monochromatic Light* [PDF]

, 1949
J. Rand McNally, Paul Griffin, L. Elkin Burkhart   +2 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

600 Medical Don'ts; or the Physician's Utility Enhanced. [PDF]

, 1888

openalex   +1 more source

Learning a Deep Single Image Contrast Enhancer from Multi-Exposure Images

IEEE Transactions on Image Processing, 2018
Jianrui Cai, Shuhang Gu, Lei Zhang
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Enhanced Oxidation of α-Glycerophosphate by Mitochondria of Thyroid-fed Rats

, 1959
Ya‐Pin Lee, A.E. Takemori, Henry A. Lardy   +2 more
openalex   +1 more source