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RNA as performance-enhancers for dendritic cells
Expert Opinion on Biological Therapy, 2010Although studies have demonstrated that antigen-loaded dendritic cells (DC) elicit antigen-specific immune responses, the clinical benefit from DC-based cancer immunotherapy remains low. RNA, in the form of mRNA, has not only been used as a source of antigen but more recently as a way to stimulate DC to produce immunostimulatory molecules.
David, Boczkowski, Smita, Nair
openaire +2 more sources
Direct Selection of Fluorescence-Enhancing RNA Aptamers
Journal of the American Chemical Society, 2018RNA aptamers that generate a strong fluorescence signal upon binding a nonfluorescent small-molecule dye offer a powerful means for the selective imaging of individual RNA species. Unfortunately, conventional in vitro discovery methods are not efficient at generating such fluorescence-enhancing aptamers, because they primarily exert selective pressure ...
Michael Gotrik +5 more
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Non-coding RNA enhances cardiac development
Journal of Molecular and Cellular Cardiology, 2014Patrick Hofmann, Reinier A. Boon
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Complementary Alu sequences mediate enhancer–promoter selectivity
Nature, 2023Liang Liang, Changchang Cao, Ji Lei
exaly
RNA-Mediated Feedback Control of Transcriptional Condensates
Cell, 2021Jonathan E Henninger +2 more
exaly
RNA Exosome-Regulated Long Non-Coding RNA Transcription Controls Super-Enhancer Activity
Cell, 2015Jiguang Wang +2 more
exaly
Extended and exposed enhancer RNAs activate transcription
Nature Structural & Molecular Biology, 2022openaire +2 more sources
Enhancer function: new insights into the regulation of tissue-specific gene expression
Nature Reviews Genetics, 2011Chin-Tong Ong, Victor G Corces
exaly

