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Untargeted Metabolomics Uncovers Food Safety Risks: Polystyrene Nanoplastics Induce Metabolic Disorders in Chicken Liver. [PDF]
Hu X +11 more
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RAPID LEUCINE‐ENKEPHALIN SYNTHESIS
International Journal of Peptide and Protein Research, 1980Leucine‐enkephalin, a naturally occurring pentapeptide with morphine‐like activity, has been synthesized by a fragment condensation liquid phase method using 3,3,4‐trimethyl‐Δ3‐phospholene‐1,1‐dichloride as a coupling agent. The advantages of this method are discussed.
E, Vilkas, M, Vilkas, J, Sainton
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Crystal structure of leucine-enkephalin
Nature, 1983The crystal structure of leucine-enkephalin has been determined in a crystal form that has four independent enkephalin molecules and much water and dimethylformamide solvent in the asymmetric unit. All four enkephalins have extended peptide backbones with the Tyr, Phe and Leu side chains above and below the plane of the backbone. There is evidence that
A, Camerman +4 more
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Monoclonal antibodies to leucine enkephalin
Biochemical and Biophysical Research Communications, 1983Monoclonal antibodies to leucine enkephalin have been produced after fusion of mouse myeloma cells with spleen cells from hyper-immune mice. Hybrid clones 2D1 and SL1 were characterised using radioimmunoassay and an enzyme-linked immunosorbent assay. The antibody 2D1 was of low affinity and showed a maximum sensitivity of 0.1ng.
C A, Jones, D P, Lane, J, Hughes
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Rapid Communications in Mass Spectrometry, 2002
Abstract We have examined the multi‐stage collision induced dissociation (CID) of metal cationized leucine enkephalin, leucine enkephalin amide, and the N‐acetylated versions of the peptides using ion trap mass spectrometry. In accord with earlier studies, the most prominent species observed during the multi‐stage
Barr, J. M., Van Stipdonk, Michael J.
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Abstract We have examined the multi‐stage collision induced dissociation (CID) of metal cationized leucine enkephalin, leucine enkephalin amide, and the N‐acetylated versions of the peptides using ion trap mass spectrometry. In accord with earlier studies, the most prominent species observed during the multi‐stage
Barr, J. M., Van Stipdonk, Michael J.
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Leucine enkephalin—A mass spectrometry standard
Mass Spectrometry Reviews, 2011AbstractThe present article reviews the mass spectrometric fragmentation processes and fragmentation energetics of leucine enkephalin, a commonly used peptide, which has been studied in detail and has often been used as a standard or reference compound to test novel instrumentation, new methodologies, or to tune instruments.
Sztáray, Judit +3 more
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Life Sciences, 1983
Methionine-enkephalin(met-enkephalin)-, leucine-enkephalin(leu-enkephalin)-, methionine-enkephalin-Arg6-Phe7(met-enkephalin-Arg-Phe)- and methionine-enkephalin-Arg6-Gly7-Leu8(met-enkephalin-Arg-Gly-Leu)-like immunoreactivities(-LI) were studied in 16 pheochromocytomas by radioimmunoassays (RIAs) for these four opioid peptides. Met-enkephalin-Arg-Phe-LI
T, Yoshimasa +5 more
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Methionine-enkephalin(met-enkephalin)-, leucine-enkephalin(leu-enkephalin)-, methionine-enkephalin-Arg6-Phe7(met-enkephalin-Arg-Phe)- and methionine-enkephalin-Arg6-Gly7-Leu8(met-enkephalin-Arg-Gly-Leu)-like immunoreactivities(-LI) were studied in 16 pheochromocytomas by radioimmunoassays (RIAs) for these four opioid peptides. Met-enkephalin-Arg-Phe-LI
T, Yoshimasa +5 more
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A heterocyclic analog of leucine‐enkephalin
Journal of Heterocyclic Chemistry, 1987AbstractA series of di‐, tri‐, tetra‐ and pentapeptide analogs of leucine‐enkephalin have been prepared in which the initial tyrosinylglycine fragment has been replaced by the 5,6‐dihydro‐5,5‐dimethyl‐2‐oxo‐3‐phenyl‐1(2H)‐pyrazineacetic acid moiety.
Albert A. Carr +4 more
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