Results 71 to 80 of about 20,669 (211)

Unveiling the Molecular Profile and Antiviral Potential of Costus arabicus L. Against Zika Virus

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
Analysis of the chemical profile and antiviral potential of Costus arabicus L. extracts. ABSTRACT Widely used in Brazilian folk medicine, Costus arabicus L. (Canarana) is a herbaceous plant with promising pharmacological potential. Here, we profile the molecular composition of extracts from different plant organs and evaluate their in vitro activity ...
Alice Rhelly V. Carvalho, José Diogo E. Reis, Ariane Coelho Ferraz, Marília Bueno da Silva Menegatto, Juliana da C. Lopes, Sônia das G. S. R. Pamplona, Milton N. da Silva, Cintia Lopes de Brito Magalhães, Paulo Wender P. Gomes, Consuelo Yumiko Yoshioka e Silva   +9 more
wiley   +1 more source

Switched-angle spinning applied to bicelles containing phospholipid-associated peptides [PDF]

, 2018
In a model study, the proton NMR spectrum of the opioid pentapeptide leucine-enkephalin associated with bicelles is investigated. The spectral resolution for a static sample is limited due to the large number of anisotropic interactions, in particular ...
Hunkeler, Andreas, Meier, Beat, Williamson, Philip, Zandomeneghi, Giorgia   +3 more
core  

Linking Metabolomic Diversity to Pharmacological Potency in Anonidium mannii Leaf Extracts

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
This study investigates the metabolomic profile and pharmacological activities of extracts from Anonidium mannii leaves. The extracts were profiled using an integrated LC‐MS/GC‐MS, and evaluated for antimicrobial, antioxidant and cytotoxic activities, providing a basis for future studies and validation in more advanced biological models.
Olusesan Ojo, Garland K. More, Gerhard Prinsloo   +2 more
wiley   +1 more source

Research of the analgesic effects and central nervous system impact of electroacupuncture therapy in rats with knee osteoarthritis

Heliyon
It aimed to observe the effects of TongDu TiaoShen (TDTS) electroacupuncture (EA) on the analgesia and central system of knee osteoarthritis (KOA) rats and explore its mechanism. SD rats were rolled into the blank group, model group (KOA), control group (
Xiahai Zheng, Jing Lin, Zhenzhen Wang, Zhenming Zeng, Haoxiong Chen   +4 more
doaj   +1 more source

Comprehensive monitoring of organic micro-pollutants in surface and groundwater in the surrounding of a solid-waste treatment plant of Castellón, Spain [PDF]

, 2016
The solid-waste treatment plant of RECIPLASA is located in the municipality of Onda (Castellón province), which is an important agricultural area of Spain, with predominance of citrus crops.
Albarrán, Fernando, Barreda, Mercedes, Cervera Vidal, María Inés, Hernandez, Felix, Ibáñez, Maria, Lopez, Francisco, Morell, Ignacio, Pitarch, Elena, Portoles, Tania, Renau-Pruñonosa, Arianna   +9 more
core   +2 more sources

Design of Experiments (DoE)‐Optimized Polymeric Oxytocin Nanoparticles for Enhanced Nose‐to‐Brain Delivery

Small, Volume 22, Issue 8, 6 February 2026.
Intranasal (IN) delivery of PEGylated PLGA nanoparticles (NPs) loaded with oxytocin (OT) (OT‐NP‐PEG) is investigated as a strategy to enhance OT transport to the brain for treating autism and other neuropsychiatric disorders. The optimized NP formulation demonstrates appropriate physicochemical characteristics, improved stability, and enhanced mucosal ...
Naveed Ahmad, Shunping Han, Rifka Utami, Rafal Baker, Dina Helal, Zhuoni Li, Mark Tricklebank, Yannis Paloyelis, Julie Wang, Marija M. Petrinovic, Sukhi Bansal, Khuloud T. Al‐Jamal   +11 more
wiley   +1 more source

Direct Analysis of Silk Dyes from the Murong Zhi Tomb from the Tang Dynasty Using Desorption Electrospray Ionization High-Resolution Mass-Spectrometry Imaging (DESI-MSI)

Separations
The identification of dyes in ancient textiles is crucial for provenance research and scientific conservation. However, the extremely significant value of these cultural relics necessitates the use of non-destructive analytical techniques. To establish a
Qian Yu, Feng Zhang, Wenchao Lv, Yan Wang, Lei Zhong, Wenting Gu, Junmei Liu, Xinyan Liu, Donghui Xu, Guangyang Liu, Guoke Chen, Nasi Ai   +11 more
doaj   +1 more source

Investigation of pharmaceuticals in processed animal by-products by liquid chromatography coupled to high-resolution mass spectrometry [PDF]

, 2016
There is an on-going trend for developing more sustainable salmon feed in which traditionally applied marine feed ingredients are replaced with alternatives.
Alm, Martin, Berntssen, Marc H. G., Bijlsma, Lubertus, Boix Sales, Clara, Hannisdal, Rita, Hernandez, Felix, Ibáñez, Maria, Lunestad, Bjorn Tore, Nácher Mestre, Jaime, Serrano, Roque   +9 more
core   +2 more sources

Updating the list of known opioids through identification and characterization of the new opioid derivative 3,4-dichloro-N- (2-(diethylamino)cyclohexyl)-N- methylbenzamide (U-49900) [PDF]

, 2017
New psychoactive substances have been rapidly growing in popularity in the drug market as non-illegal drugs. In the last few years, an increment has been reported on the use of synthetic alternatives to heroin, the synthetic opioids.
Carbón, X., Fabregat-Safont, David, Fornís, I., Guillamón, Eva, Hernandez, Felix, Ibáñez, Maria, Sancho, Juan V, Ventura, Mireia   +7 more
core   +1 more source

Molecular Aspect of Annelid Neuroendocrine system

, 2007
Hormonal processes along with enzymatic processing similar to that found in vertebrates occur in annelids. Amino acid sequence determination of annelids precursor gene products reveals the presence of the respective peptides that exhibit high sequence ...
Salzet, M.
core   +1 more source