Automated delineation of enlarged perivascular spaces (EPVS) [PDF]
AbstractBackgroundEnlarged Perivascular Spaces (EPVS) are associated with small vessel disease. The objective of this study was to develop semi‐automated techniques for the quantification of EPVS burden.MethodAn intensity‐based threshold was used to identify EPVS.
Mohammed Goryawala +4 more
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Enlarged perivascular spaces in multiple sclerosis on magnetic resonance imaging: a systematic review and meta-analysis [PDF]
BACKGROUND Perivascular spaces can become detectable on magnetic resonance imaging (MRI) upon enlargement, referred to as enlarged perivascular spaces (EPVS) or Virchow-Robin spaces. EPVS have been linked to small vessel disease.
Tobias Granberg +2 more
exaly +3 more sources
Protoplasmic Perivascular Astrocytes Play a Crucial Role in the Development of Enlarged Perivascular Spaces in Obesity, Metabolic Syndrome, and Type 2 Diabetes Mellitus [PDF]
Astrocytes (ACs) are the most abundant cells in the brain and, importantly, are the master connecting and communicating cells that provide structural and functional support for brain cells at all levels of organization.
Melvin Hayden, Hayden Melvin R
exaly +2 more sources
Enlarged basal ganglia perivascular spaces and sleep parameters. A population-based study [PDF]
Perivascular spaces (PVS) are involved in mechanisms of brain interstitial fluid and metabolic waste clearance. Since most of this clearance occurs during sleep, it is plausible that sleep-related disorders favor PVS dilatation.
Pablo Castillo +2 more
exaly +2 more sources
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Automated method for segmenting enlarged perivascular spaces
Alzheimer's & Dementia, 2022AbstractBackgroundEnlarged perivascular spaces (ePVS) on magnetic resonance (MR) imaging are difficult to quantify due to their small size, diffuse distribution, and often, high prevalence. We present a method for automating ePVS volume quantification in the basal ganglia.MethodVanderbilt Memory and Aging Project participants (n=327, 73±7, 41% female ...
Corey W. Bown +10 more
openaire +1 more source
Enlarged perivascular spaces are associated with white matter injury, cognition and inflammation in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy [PDF]
Enlarged perivascular spaces have been previously reported in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, but their significance and pathophysiology remains unclear.
Daniel Schwartz +2 more
exaly +3 more sources
The existence of lymphatic vessels or similar clearance systems in the central nervous system (CNS) that transport nutrients and remove cellular waste is a neuroscientific question of great significance. As the brain is the most metabolically active organ in the body, there is likely to be a potential correlation between its clearance system and the ...
Jun, Zhang +7 more
openaire +2 more sources
MRI-visible enlarged perivascular spaces
Neurology, 2020Intracerebral hemorrhage (ICH) is the most severe stroke subtype, associated with high risk of death and dependence.1 Oral anticoagulants (OACs) increase risk for ICH and lead to more severe and more frequently fatal bleeds than spontaneous ICH.2 Thus developing a predictive model for stratifying the risk of ICH in patients eligible for OAC has ...
Nicolas Raposo, Anand Viswanathan
openaire +3 more sources

