Results 61 to 70 of about 744,448 (280)
Information Guide: Enlargement Policy [PDF]
, 2013 A guide to the European Union’s Enlargement Policy, with hyperlinks to sources of information within European Sources Online and on external ...
Cardiff EDC, .
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
European Union and the Challenges of Globalization [PDF]
Romanian Journal of European Affairs, 2006 The paper analyzes the current implications of globalization on the European Union. While the EU recorded significant successes mainly in the filed of integration and enlargement, the implications of globalization seem rather worrisome.
Florin Bonciu
doaj
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Enlargement: A Process rather than a Point in Time. CEPS Policy Briefs No. 51, 1 April 2004 [PDF]
, 2004 The 1st of May 2004 is being marked by numerous important political events, speeches and festivities. This is appropriate in the sense that on that day ten new member states join the EU.
Crum, Ben, Gros, Daniel, Turmann, Anna.
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Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari +9 more
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Gay Rights in the EU: A Long Way Forward For the Union of 27
Croatian Yearbook of European Law and Policy, 2007 This article provides a summary of the evolution of gay rights in the European Union. It highlights some legal lacunae in the protection of these rights which should be dealt with, and provides a sketch of the necessary developments in the near future ...
Dimitry Kochenov
doaj +1 more source