Results 81 to 90 of about 487,006 (336)

Enlargement

open access: yes, 2021
This chapter argues that the European union's (EU’s) eastwards expansion in particular marked a watershed moment in the development of the EU’s enlargement policy, and that this had momentous consequences for gender equality policy in the new member states.
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Knocking NATO: Strategic and institutional challenges risk the future of Europe’s seven-decade long cold peace

open access: yesThe School of Public Policy Publications, 2019
Despite providing European stability through collective defence and crisis management in an exclusive club, NATO faces persistent challenges from strategic insecurities complicated by recent institutional uncertainties.
Anessa L. Kimball
doaj   +1 more source

Influence of the EU enlargement on the agrarian foreign trade development in member states

open access: yesAgricultural Economics (AGRICECON), 2009
The paper analyses the development of agrarian foreign trade of the EC/EU states in the period 1961-2006. The aim of the analysis is to evaluate the influence of the EC/EU member base enlargement on the development of the value and territorial structure ...
M. Svatoš, L. Smutka
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

EU enlargement and the Common Agricultural Policy

open access: yesAgricultural Economics (AGRICECON), 2003
The incorporation of the Central and Eastern European Countries (CEECs) to the common agrarian market of the European Union is an entrance the saturated market solving problems with surpluses of main agricultural commodities. That is why an increasing of
V. Bečvářová
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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