Results 111 to 120 of about 100,569 (330)

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Effects of El Niño on the dynamics of Lake Alchichica, central Mexico

Geofísica Internacional, 2003
Se presenta evidencia empírica que muestra los efectos contemporáneos del fenómeno El Niño Oscilación del Sur sobre Alchichica, un lago profundo, monomíctico cálido.
Javier Alcocer, Alfonso Lugo
doaj   +1 more source

Association of the genetic polymorphisms of the ACE gene and the eNOS gene with lupus nephropathy in northern Chinese population

BMC Medical Genetics, 2010
BackgroundIt has been reported that some single nucleotide polymorphisms (SNPs) of the angiotensin converting enzyme (ACE) gene and the endothelial nitric oxide synthase (eNOS) gene are associated with the development of systemic lupus erythematosus (SLE)
X. Li, J. An, R. Guo, Z. Jin, Y. Li, Y. Zhao, F. Lu, H. Lian, P. Liu, Y. Zhao, X. Jin   +10 more
semanticscholar   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Micro‐ and nanomotors in biomedical applications

Responsive Materials, EarlyView.
Micro‐ and nanomotors (MNMs), as autonomous devices converting chemical or external energy into mechanical propulsion, have emerged as transformative drug delivery platforms in biomedicine. This review systematically outlines the design principles governing MNMs' propulsion and operation, highlights the applications of MNMs in disease treatment, and ...
Xiangyu Meng, Yuqi Tang, Quan Li
wiley   +1 more source

Noninvasive electrical stimulation enhances the diabetic osseointegration via alleviating mitochondrial damage

VIEW, EarlyView.
A high‐glucose environment induced an imbalance in mitochondrial homeostasis, which resulted in the inhibition of bone tissue regeneration. In this study, we first introduce the exogenous noninvasive direct current electric field (DCEF) strategy for regulating mitochondrial homeostasis and explore its effect on bone regeneration in high‐glucose ...
Dongzong Huang, Rongchen Xu, Changzhen Xu, Peng Xue, Lin Liu, Yiping Fan, Miaoshen Guan, Menglin Luo, Shaoyuan Cui, Xiaoyu Wang, Jin Liu, Chunyu Zhang, Bo Fu, Hua Jiang, Hongbo Li   +14 more
wiley   +1 more source

On the Morphology of Toponyms: What Greek Inflectional Paradigms Can Teach us

Transactions of the Philological Society, Volume 123, Issue 1, Page 77-96, March 2025.
Abstract The research is a contribution to the investigation of the grammatical status of toponyms from the point of view of inflectional paradigmatic morphology. By examining data from Standard Modern Greek, as well as select data from its historical development, the analysis reveals that the inflectional morphology of toponyms shows significant ...
Michail I. Marinis
wiley   +1 more source

Effects of Nitric Oxide Synthase Isoforms During Experimental Tooth Movement

Turkish Journal of Orthodontics, 2012
Aim:Many systemic/local factors take part in the process of bone-remodeling. Nitric oxide (NO), an important intercellular signal modulator produced by osteoblasts, is a potent regulator of bone-remodeling.
Hasan Bülbül, Hüseyin Ölmez, Erol Akın, Sıla Mermut Gökçe, Şeniz Karaçay, Mehmet Kürkçü   +5 more
doaj   +1 more source

Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex

Diabetes, 2012
Vascular dysfunction that accompanies obesity and insulin resistance may be mediated by lipid metabolites. We sought to determine if vascular ceramide leads to arterial dysfunction and to elucidate the underlying mechanisms. Pharmacological inhibition of
Quanjiang Zhang, W. Holland, Lloyd Wilson, J. Tanner, Devin Kearns, Judd M. Cahoon, D. Pettey, Jason T. Losee, B. Duncan, D. Gale, C. Kowalski, Nicholas Deeter, Alexandrea Nichols, Michole Deesing, Colton Arrant, T. Ruan, C. Boehme, D. McCamey, J. Rou, K. Ambal, Krishna K. Narra, S. Summers, E. Abel, J. Symons   +23 more
semanticscholar   +1 more source

Senescent Macrophages Promote Age‐Related Revascularization Impairment by Increasing Antiangiogenic VEGF‐A165B Expression

Aging Cell, EarlyView.
The underlying mechanisms of age‐related revascularization impairment are not clear. Our research firstly identified that macrophages were more senescent in the ischemic skeletal muscle of old mice and senescent macrophages could inhibit revascularization.
Minghong Chen, Junyu Chen, Yu Liu, Xuerui Wang, Meilian Yao, Jing Chen, Jian Zhang, Qun Huang   +7 more
wiley   +1 more source