Results 141 to 150 of about 100,569 (330)

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

open access: yesCell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang   +4 more
wiley   +1 more source

The role of adipose tissue cell elements in the regulation of the nitroxidergic system and possible ways of pharmacological modulation

open access: yesСучасні медичні технології
Endothelial dysfunction is characterized by a decrease in the bioavailability of the vasodilator – nitric oxide (NO), and an increase in the level of vasoconstrictor substances.
I. F. Bielenichev   +6 more
doaj   +1 more source

Vascular nitric oxide: Beyond eNOS.

open access: yesJournal of Pharmacological Sciences, 2015
Yingzi Zhao, P. Vanhoutte, S. Leung
semanticscholar   +1 more source

The Dialectic of Backsliding: Thinking with Habermas About Democratic Progress and Regression

open access: yesEuropean Journal of Philosophy, EarlyView.
Abstract There is widespread agreement that we are living in an age of “democratic backsliding,” in which a growing number of formally democratic countries are falling behind previously achieved levels of democratization. But on what grounds can we claim that one level of democratic development is “higher” or “lower” than another?
Fabio Wolkenstein
wiley   +1 more source

Variabilidad espacial y temporal de la temperatura del aire en la zona cafetera colombiana

open access: yesInvestigaciones Geográficas, 2016
La zona cafetera colombiana está ubicada en- teramente en el hemisferio norte, entre los 1 y 11° grados de latitud, sobre la cordillera de los Andes.
Edna Paola Pérez Rendón   +2 more
doaj  

Developing a Two‐Sided Decision Box to Facilitate Shared Decision‐Making for Switching From Conventional to Pharmacokinetic‐Tailored Prophylaxis in Haemophilia

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Decision‐making in haemophilia is challenging due to the small evidence base, disease heterogeneity, and inter‐patient variability. Shared decision‐making (SDM) supports patient‐clinician decisions. Aim Creation of a two‐sided decision box facilitating SDM for haemophilia patients switching from conventional (weight‐based) to ...
Arun Keepanasseril   +4 more
wiley   +1 more source

Canagliflozin protects cardiovascular function in type 2 diabetic coronary artery disease by regulating natriuretic peptide B

open access: yesJournal of Diabetes Investigation, EarlyView.
Canagliflozin regulated the cyclic guanosine monophosphate (cGMP)‐protein kinase 1‐α signaling pathway through the natriuretic peptide B gene, thereby improving cell viability, apoptosis, and reactive oxygen species levels, and ultimately protecting cardiac function in type 2 diabetic patients with coronary artery disease.
Jiarui Zhang   +5 more
wiley   +1 more source

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