Results 11 to 20 of about 100,569 (330)

eNOS at a glance [PDF]

open access: yesJournal of Cell Science, 2004
Endothelium-derived nitric oxide (NO) is a critical regulator of cardiovascular homeostasis. Endothelial nitric oxide synthase (eNOS or NOS3)-derived NO is an endogenous vasodilatory gas that continually regulates the diameter of blood vessels and maintains an anti-proliferative and anti ...
W. Sessa
openaire   +3 more sources

Increased eNO and pulmonary iNOS expression in eNOS null mice [PDF]

open access: bronzeEuropean Respiratory Journal, 2003
Nitric oxide (NO) is a major regulatory molecule of the cardiovascular system; however, measurement of vascular NO synthesisin vivorepresents a major challenge. NO stemming from the lower respiratory tract has been used as a marker of vascular endothelial function. Experimental evidence for this concept is lacking.
Stéphane Cook   +5 more
openalex   +4 more sources

Endothelial dysfunction due to eNOS uncoupling: molecular mechanisms as potential therapeutic targets

open access: yesCellular & Molecular Biology Letters, 2023
Nitric oxide (NO) is one of the most important molecules released by endothelial cells, and its antiatherogenic properties support cardiovascular homeostasis.
Anna Janaszak-Jasiecka   +4 more
semanticscholar   +1 more source

Endothelial Nitric Oxide Synthase (eNOS) and the Cardiovascular System: in Physiology and in Disease States

open access: yesAmerican Journal of Biomedical Science & Research, 2022
Endothelial nitric oxide synthase (eNOS) plays a critical role in regulating and maintaining a healthy cardiovascular system. The importance of eNOS can be emphasized from the genetic polymorphisms of the eNOS gene, uncoupling of eNOS dimerization, and ...
N. Tran   +5 more
semanticscholar   +1 more source

Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure

open access: yesCirculation, 2021
Supplemental Digital Content is available in the text. Background: Current paradigms suggest that nitric oxide (NO) produced by endothelial cells (ECs) through endothelial nitric oxide synthase (eNOS) in the vessel wall is the primary regulator of blood ...
Francesca Leo   +21 more
semanticscholar   +1 more source

ENO Reconstruction and ENO Interpolation Are Stable [PDF]

open access: yesFoundations of Computational Mathematics, 2012
We prove stability estimates for the ENO reconstruction and ENO interpolation procedures. In particular, we show that the jump of the reconstructed ENO pointvalues at each cell interface has the same sign as the jump of the underlying cell averages across that interface.
Ulrik Skre Fjordholm   +2 more
openaire   +3 more sources

eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally [PDF]

open access: yesAmerican Journal of Physiology-Lung Cellular and Molecular Physiology, 2006
At birth, the transition to gas breathing requires the function of endothelial vasoactive agents. We investigated the function of endothelial nitric oxide synthase (eNOS) in pulmonary artery (PA) vessels and endothelial cells isolated from fetal and young (4-wk) sheep. We found greater relaxations to the NOS activator A-23187 in 4-wk-old compared with
James A. Russell   +7 more
openaire   +2 more sources

Indexes of nitric oxide system in experimental antiphospholipid syndrome [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2020
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence of antibo­dies to negatively charged membrane phospholipids (aPL).
O. Z. Yaremchuk   +5 more
doaj   +1 more source

New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease

open access: yesInternational Journal of Molecular Sciences, 2019
The Global Burden of Disease Study identified cardiovascular risk factors as leading causes of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism that is associated with most of these risk factors and stressors, and ...
A. Daiber   +7 more
semanticscholar   +1 more source

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