Background: Patients with treatment-resistant hypertension have a worse cardiovascular prognosis compared to those who achieve their target levels of blood pressure (BP). One of biochemical and clinical markers of a decreased response to antihypertensive
Aleksandr N. Stafeev +2 more
doaj +1 more source
Correlation of Endothelial Nitric Oxide Synthase Gene Polymorphism (GG, TT and GT Genotype) with Proteinuria and Retinopathy in Type 2 Diabetic Patients [PDF]
Background: Nephropathy is the most important leading cause of end stage renal failure in type 2 diabetic patients, so numerous studies were done to diagnose and evaluate risk factors of diabetic nephropathy (DN).
Ali Momeni +3 more
doaj +1 more source
Estrogen-dependent dynamic profile of eNOS-DNA associations in prostate cancer [PDF]
In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estrogen Receptor Beta (ERβ) and Hypoxia Inducible Factors (HIFs) that determine localized chromatin remodeling ...
A Grasselli +66 more
core +3 more sources
Tonic and phasic nitric oxide signals in hippocampal long-term potentiation [PDF]
Nitric oxide ( NO) participates in long-term potentiation (LTP) and other forms of synaptic plasticity in many different brain areas but where it comes from and how it acts remain controversial.
Garthwaite, J, Hopper, RA
core +1 more source
Enabling onshore CO2 storage in Europe: fostering international cooperation around pilot and test sites [PDF]
To meet the ambitious EC target of an 80% reduction in greenhouse gas emissions by 2050, CO2 Capture and Storage (CCS) needs to move rapidly towards full scale implementation with geological storage solutions both on and offshore.
Audigane, Pascal D. +9 more
core +4 more sources
The effect of eight weeks of endurance training along with cinnamon extract consumption on expression of angiogenic markers in endothelial dysfunction of the coronary arteries in streptozotocin-diabetic male rats [PDF]
Purpose: Angiogenesis refers to the formation of new blood vessels from existing vessels, which is an important event in various physiological processes.
Amir Houshang Monzemi +3 more
doaj +1 more source
eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering. [PDF]
This study evaluates the durability of a novel tissue engineered blood vessel (TEBV) created by seeding a natural vascular tissue scaffold (decellularized human saphenous vein allograft) with autologous adipose-derived stem cells (ASC) differentiated ...
Bagameri, Gabor +10 more
core +2 more sources
Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]
Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed +5 more
core +2 more sources
Examining the role of insulin in the regulation of cardiovascular health [PDF]
A substantial body of evidence has reported that insulin has direct actions on the cardiovascular system independent of its systemic effects on plasma glucose or lipids.
Salt, Ian P.
core +1 more source
Coronary heart disease (CHD) is a major cause of mortality. Morphological substrate of CHD in most cases is atherosclerosis, which is based on structural genes polymorphism eNOS and AGTR2.
A. L. Khokhlov +4 more
doaj +1 more source

