Results 11 to 20 of about 100,569 (330)
Endothelium-derived nitric oxide (NO) is a critical regulator of cardiovascular homeostasis. Endothelial nitric oxide synthase (eNOS or NOS3)-derived NO is an endogenous vasodilatory gas that continually regulates the diameter of blood vessels and maintains an anti-proliferative and anti ...
W. Sessa
openaire +3 more sources
Increased eNO and pulmonary iNOS expression in eNOS null mice [PDF]
Nitric oxide (NO) is a major regulatory molecule of the cardiovascular system; however, measurement of vascular NO synthesisin vivorepresents a major challenge. NO stemming from the lower respiratory tract has been used as a marker of vascular endothelial function. Experimental evidence for this concept is lacking.
Stéphane Cook+5 more
openalex +4 more sources
Nitric oxide (NO) is one of the most important molecules released by endothelial cells, and its antiatherogenic properties support cardiovascular homeostasis.
Anna Janaszak-Jasiecka+4 more
semanticscholar +1 more source
Endothelial nitric oxide synthase (eNOS) plays a critical role in regulating and maintaining a healthy cardiovascular system. The importance of eNOS can be emphasized from the genetic polymorphisms of the eNOS gene, uncoupling of eNOS dimerization, and ...
N. Tran+5 more
semanticscholar +1 more source
Supplemental Digital Content is available in the text. Background: Current paradigms suggest that nitric oxide (NO) produced by endothelial cells (ECs) through endothelial nitric oxide synthase (eNOS) in the vessel wall is the primary regulator of blood ...
Francesca Leo+21 more
semanticscholar +1 more source
ENO Reconstruction and ENO Interpolation Are Stable [PDF]
We prove stability estimates for the ENO reconstruction and ENO interpolation procedures. In particular, we show that the jump of the reconstructed ENO pointvalues at each cell interface has the same sign as the jump of the underlying cell averages across that interface.
Ulrik Skre Fjordholm+2 more
openaire +3 more sources
eNOS function is developmentally regulated: uncoupling of eNOS occurs postnatally [PDF]
At birth, the transition to gas breathing requires the function of endothelial vasoactive agents. We investigated the function of endothelial nitric oxide synthase (eNOS) in pulmonary artery (PA) vessels and endothelial cells isolated from fetal and young (4-wk) sheep. We found greater relaxations to the NOS activator A-23187 in 4-wk-old compared with
James A. Russell+7 more
openaire +2 more sources
Indexes of nitric oxide system in experimental antiphospholipid syndrome [PDF]
Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the presence of antibodies to negatively charged membrane phospholipids (aPL).
O. Z. Yaremchuk+5 more
doaj +1 more source
The Global Burden of Disease Study identified cardiovascular risk factors as leading causes of global deaths and life years lost. Endothelial dysfunction represents a pathomechanism that is associated with most of these risk factors and stressors, and ...
A. Daiber+7 more
semanticscholar +1 more source