Results 31 to 40 of about 61,209 (165)

Say NO to ROS: Their Roles in Embryonic Heart Development and Pathogenesis of Congenital Heart Defects in Maternal Diabetes

open access: yesAntioxidants, 2019
Congenital heart defects (CHDs) are the most prevalent and serious birth defect, occurring in 1% of all live births. Pregestational maternal diabetes is a known risk factor for the development of CHDs, elevating the risk in the child by more than four ...
Anish Engineer   +3 more
doaj   +1 more source

Catechins inhibit atherosclerosis in male rats on a high fat diet

open access: yesUniversa Medicina, 2015
Background A catechin isolate from the green tea clone GMB 4, which shows antioxidant activity, may be a candidate drug for prevention of atherosclerosis.
Erna Susanti   +2 more
doaj   +1 more source

Influence of endothelial NO synthase gene polymorphisms on development and prognosis of chronic heart failure

open access: yesКардиоваскулярная терапия и профилактика, 2008
Aim. To study the effects of eNOS gene polymorphisms (Glu298Asp and VNTR intron 4) on endothelial dysfunction (ED) development, chronic heart failure (CHF) severity and progression in patients with coronary heart disease (CHD) and arterial hypertension ...
N. F. Yakovleva   +7 more
doaj  

CT-1 induces angiogenesis by regulating the ADMA/DDAH Pathway

open access: yesBiomedical Papers, 2015
Background. Cardiotrophin-1 (CT-1), a member of the IL-6 superfamily, is elevated in the serum of patients with ischemic and valvular heart disease. In this study, we hypothesized that CT-1 induces endothelial cell angiogenesis and that the ADMA/DDAH ...
Zhen Zhong Zheng   +3 more
doaj   +1 more source

The efficacy of nitric oxide in stroke (ENOS) trial – where do we stand in Romania? [PDF]

open access: yesRomanian Journal of Neurology, 2012
Introduction. Romania ranks third worldwide for stroke mortality. Although high blood pressure (BP) is a major risk factor for stroke incidence and determinant of outcome, the management of BP in acute stroke remains undefined. The present study assesses
Szocs Ildiko   +7 more
doaj   +1 more source

Numerical experiments on the accuracy of ENO and modified ENO schemes [PDF]

open access: yesJournal of Scientific Computing, 1990
Numerical experiments show an accuracy degeneracy phenomena in essentially nonoscillatory (ENO) finite difference schemes for hyperbolic conservation laws [cf. \textit{A. M. Rogerson} and \textit{E. Meiburg}, ibid. 5, No.2, 151-167 (1990; Zbl 0732.65086)].
openaire   +2 more sources

Calidad biológica y fisicoquímica de tres fuentes de agua y su relación con el fenómeno de El Niño y La Niña

open access: yesRevista U.D.C.A Actualidad & Divulgación Científica, 2019
En el municipio de El Carmen de Viboral, Antioquia, la cuenca de la quebrada La Cimarronas y sus afluentes Los Andes y La Madera son las principales fuentes de abastecimiento del acueducto de la localidad.
Yimmy Montoya-Moreno   +3 more
doaj   +1 more source

Endothelial nitric oxide synthase dimerization is regulated by heat shock protein 90 rather than by phosphorylation. [PDF]

open access: yesPLoS ONE, 2014
Endothelial nitric oxide synthase (eNOS) is a multifunctional enzyme with roles in diverse cellular processes including angiogenesis, tissue remodeling, and the maintenance of vascular tone.
Weiguo Chen   +5 more
doaj   +1 more source

Differential effects of heat shock protein 90 and serine 1179 phosphorylation on endothelial nitric oxide synthase activity and on its cofactors. [PDF]

open access: yesPLoS ONE, 2017
Endothelial nitric oxide synthase (eNOS) is responsible for maintaining systemic blood pressure, vascular remodeling and angiogenesis. Previous studies showed that bovine eNOS serine 1179 (Serine 1177 for human eNOS) phosphorylation enhanced NO synthesis.
Yuanzhuo Chen   +4 more
doaj   +1 more source

REALITIES AND PROSPECTS FOR PHARMACOLOGICAL CORRECTION OF «ADMA-ENOS"-ASSOCIATED WAYS IN PREECLAMPSIA

open access: yesРациональная фармакотерапия в кардиологии, 2016
Methylated analogs of L-arginine - asymmetric dimetilarginin (ADMA) and monometilarginin (L-NMMA) - are endogenous inhibitors of endothelial NO-synthase (eNOS). ADMA level in maternal plasma is increased in women with preeclampsia. The high level of ADMA
M. V. Pokrovsky   +12 more
doaj   +1 more source

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