A Hepatocyte-to-Stellate Cell Axis Couples Alternate-Day Fasting to Liver Fibrosis Resolution via ATG7 S-Nitrosylation. [PDF]
Adv Sci (Weinh)Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Wang X +17 more
europepmc +2 more sources
Alʹmanah Kliničeskoj Mediciny, 2023 Background: Patients with treatment-resistant hypertension have a worse cardiovascular prognosis compared to those who achieve their target levels of blood pressure (BP). One of biochemical and clinical markers of a decreased response to antihypertensive
Aleksandr N. Stafeev +2 more
doaj +1 more source
Correlation of Endothelial Nitric Oxide Synthase Gene Polymorphism (GG, TT and GT Genotype) with Proteinuria and Retinopathy in Type 2 Diabetic Patients [PDF]
Journal of Clinical and Diagnostic Research, 2016 Background: Nephropathy is the most important leading cause of end stage renal failure in type 2 diabetic patients, so numerous studies were done to diagnose and evaluate risk factors of diabetic nephropathy (DN).
Ali Momeni +3 more
doaj +1 more source
Estrogen-dependent dynamic profile of eNOS-DNA associations in prostate cancer [PDF]
, 2013 In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estrogen Receptor Beta (ERβ) and Hypoxia Inducible Factors (HIFs) that determine localized chromatin remodeling ...
Arturo Londono-Vallejo +55 more
core +2 more sources
This replication data is for Enos, Ryan D. and Eitan Hersh, 2015. “Campaign Perceptions of Electoral Closeness: Uncertainty, Fear, and Over-Confidence” British Journal of Political Science.
Enos, Ryan
core +4 more sources
eNOS protects from atherosclerosis despite relevant superoxide production by the enzyme in apoE mice. [PDF]
, 2012 All three nitric oxide synthase (NOS) isoforms are expressed in atherosclerotic plaques. NOS enzymes in general catalyse NO production. However, under conditions of substrate and cofactor deficiency, the enzyme directly catalyse superoxide formation ...
Sabine Grüner +27 more
core +2 more sources
The Effects of Eight Weeks High Intensity Intermittent Training and Blood Flow Restricted on Angiogenic Markers of Muscle in Male Runners [PDF]
Annals of Applied Sport Science, 2020 Background. Due to the lack of sufficient information about the interactive effects of high intensity intermittent training (HIIT) and blood flow restricted (BFR) exercises on angiogenic variables of skeletal muscle, it seems that integration these ...
Seyyed Yaser Alavi, Shadmehr Mirdar
doaj
The effects of severe hypoxia on nitric oxide parameters in hypoxia-tolerant rodent: nannospalax nehringi [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2018 Blind mole rats (BMRs) are solitary rodents which are tolerant to severe hypoxia. The aim of this study is to reveal the changes in nitric oxide (NO) and nitric oxide enzymes (NOS), which are involved in many physiological and pathological processes ...
Barış YILDIZ +6 more
doaj +1 more source
Архивъ внутренней медицины, 2016 Coronary heart disease (CHD) is a major cause of mortality. Morphological substrate of CHD in most cases is atherosclerosis, which is based on structural genes polymorphism eNOS and AGTR2.
A. L. Khokhlov +4 more
doaj +1 more source
PHARMACOGENETIC FEATURES OF THERAPY OF PATIENTS WITH ATHEROSCLEROSIS
Архивъ внутренней медицины, 2018 The complexity of therapy of lipid metabolism disorders is not only in comorbidity and polypragmasia, but also in predicting a genetically determined response to the treatment.
A. L. Khokhlov +7 more
doaj +1 more source