Results 81 to 90 of about 100,569 (330)

Beyond Histones: Unveiling the Functional Roles of Protein Acetylation in Prokaryotes and Eukaryotes

Cell Biology International, EarlyView.
ABSTRACT Lysine acetylation plays a crucial role in cellular processes and is found across various evolutionary organisms. Recent advancements in proteomic techniques revealed the presence of acetylation in thousands of non‐histone proteins. Here, we conducted extensive meta‐analysis of 48 acetylomes spanning diverse organisms, including archaea ...
Bruno Sousa Bonifácio, Ariely Barbosa Leite, Ana Caroline de Castro Nascimento Sousa, Suellen Rodrigues Maran, Antoniel Augusto Severo Gomes, Elton J. R. Vasconcelos, Nilmar Silvio Moretti   +6 more
wiley   +1 more source

Endothelial nitric oxide synthase dimerization is regulated by heat shock protein 90 rather than by phosphorylation. [PDF]

PLoS ONE, 2014
Endothelial nitric oxide synthase (eNOS) is a multifunctional enzyme with roles in diverse cellular processes including angiogenesis, tissue remodeling, and the maintenance of vascular tone.
Weiguo Chen, Hongbing Xiao, Alicia N Rizzo, Wei Zhang, Yifeng Mai, Meng Ye   +5 more
doaj   +1 more source

eNOS polymorphisms and moyamoya disease [PDF]

Child's Nervous System, 2011
Dear Editor, The recent report on eNOS polymorphisms and moyamoya disease is very interesting [1]. Park et al. reported that “pediatric and adult-onset moyamoya disease have different genetic backgrounds [1].” This observation is very interesting. Before finalized summarizing, there are some concerns. First, the investigation covered only all four main
openaire   +3 more sources

Deciphering the Binding of Caveolin-1 to Client Protein Endothelial Nitric-oxide Synthase (eNOS)

Journal of Biological Chemistry, 2014
Background: One of the most significant client proteins of Cav-1 is the endothelial nitric-oxide synthase (eNOS), but their specific binding site is unknown.
Andy E. Trane, D. Pavlov, Arpeeta Sharma, U. Saqib, K. Lau, F. van Petegem, R. Minshall, L. Roman, P. Bernatchez   +8 more
semanticscholar   +1 more source

Epigenetic Changes Related to Hypertension in Asian Adults: A Systematic Review

Chronic Diseases and Translational Medicine, EarlyView.
PRISMA study flow diagram. ABSTRACT Background Elevated high blood pressure is controlled by complicated, little‐understood genetic and epigenetic pathways that are influenced by both heritable and environmental variables. Many adult systolic and diastolic blood pressure‐related genomic loci have been identified through previous genome‐wide association
Lilik Sukesi, Yunia Sribudiani, Steven Yulius Usman, Eric Ricardo Yonatan, Ahmedz Widiasta, Noormarina Indraswari, Ria Bandiara, Nanny N. M. Soetedjo   +7 more
wiley   +1 more source

PHARMACOGENETIC FEATURES OF THERAPY OF PATIENTS WITH ATHEROSCLEROSIS

Архивъ внутренней медицины, 2018
The complexity of therapy of lipid metabolism disorders is not only in comorbidity and polypragmasia, but also in predicting a genetically determined response to the treatment.
A. L. Khokhlov, A. N. Yavorsky, N. O. Pozdnyakov, J. V. Rybachkova, E. S. Emelianov, A. A. Khokhlov, A. E. Miroshnikov, S. O. Pozdnyakov   +7 more
doaj   +1 more source

Differential effects of heat shock protein 90 and serine 1179 phosphorylation on endothelial nitric oxide synthase activity and on its cofactors. [PDF]

PLoS ONE, 2017
Endothelial nitric oxide synthase (eNOS) is responsible for maintaining systemic blood pressure, vascular remodeling and angiogenesis. Previous studies showed that bovine eNOS serine 1179 (Serine 1177 for human eNOS) phosphorylation enhanced NO synthesis.
Yuanzhuo Chen, Bojie Jiang, Yugang Zhuang, Hu Peng, Weiguo Chen   +4 more
doaj   +1 more source

PKC-Dependent Phosphorylation of eNOS at T495 Regulates eNOS Coupling and Endothelial Barrier Function in Response to G+ -Toxins

PLoS ONE, 2014
Gram positive (G+) infections make up ∼50% of all acute lung injury cases which are characterized by extensive permeability edema secondary to disruption of endothelial cell (EC) barrier integrity.
Feng Chen, Sanjiv Kumar, Yanfang Yu, S. Aggarwal, Christine M Gross, Yusi Wang, T. Chakraborty, A. Verin, J. Catravas, R. Lucas, S. Black, D. Fulton   +11 more
semanticscholar   +1 more source

Fifty years of research on the Joulters ooid sandbody—Impact on carbonate sedimentology and diagenesis and lessons learned from an invaluable analogue

The Depositional Record, EarlyView.
The Joulters ooid sandbody of northern Great Bahama Bank is a vast expanse of muddy ooid sands partly rimmed by clean ooid sands and formed into a relatively thick layer of significant extent. Knowledge of the development of depositional and diagenetic patterns in the Joulters example has forwarded our general understanding of carbonate sedimentology ...
Harris Paul
wiley   +1 more source

Effects of Silibinin on Nitric Oxide Synthase Genes Expression during Hepatic Warm Ischemia-reperfusion in Adult Male Rats

Journal of Mazandaran University of Medical Sciences, 2018
Background and purpose: Ischemia-reperfusion injuries (I/RI) are the major causes of liver failure after various types of liver surgeries, particularly liver transplantation. Reactive oxygen species (ROS) are the major causes of such injuries, therefore,
Ehsan nabipour, Vahid Akbari Kordkheyli, Soheil Azizi, Abbas Khonakdar-Tarsi   +3 more
doaj