Results 51 to 60 of about 27,602 (209)

Thromboprophylaxis with unilateral pneumatic device led to less edema and blood loss compared to enoxaparin after knee arthroplasty: randomized trial

BMC Musculoskeletal Disorders, 2022
Background Pharmacological and mechanical thromboprophylaxis are frequently used together after total knee arthroplasty (TKA). Most studies in this context compare anticoagulants versus a combination of these drugs with an intermittent pneumatic ...
João Alberto Ramos Maradei-Pereira, Marcel Lobato Sauma, Marco Kawamura Demange   +2 more
doaj   +1 more source

Prophylactic Enoxaparin Reduces Symptomatic Venous Thromboembolism Compared With No Chemoprophylaxis Within 95 Days After Knee Arthroscopy

Arthroscopy, EarlyView.
Purpose To investigate whether prophylactic use of low‐molecular‐weight heparin (enoxaparin) after knee arthroscopy reduces the incidence of symptomatic venous thromboembolism (VTE) compared with no postoperative pharmacological prophylaxis. Methods We conducted a population‐based cohort study using linked national insurance and hospital data from ...
Aylin Albrecht, Lorenz Kapral, Felix Gruber, Christoph Dibiasi, Oliver Kimberger, Christian Albrecht   +5 more
wiley   +1 more source

Magnetic Resonance Imaging Modified Dixon Fat Quantification Analysis Is a Quantitative and Reliable Method for Evaluating Fatty Atrophy of the Hamstring Muscle Complex After Proximal Avulsion Injury

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the reliability and validity of objective fat quantification using the modified Dixon magnetic resonance imaging sequence for assessing fatty degeneration in conservatively treated patients with proximal hamstring avulsion injuries. Methods Magnetic resonance imaging with modified Dixon sequence was used.
John Hanke, Philipp Schenk, Irga Kemal, Markus Heinecke, Philipp Kobbe, Thomas Mendel   +5 more
wiley   +1 more source

Optimal Dosing of Enoxaparin in Critically Ill Patients with Venous Thromboembolism

INNOVATIONS in Pharmacy, 2023
Background: Evidence suggests that goal anti-Xa levels are achieved in only 33% of critically ill patients receiving standard prophylactic enoxaparin dosing.
Aliya Abdulla, Caitlin M. Williams, Trisha N. Branan, Susan E. Smith   +3 more
doaj   +1 more source

A Review of Virtual Twins in Physiologically‐Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacology &Therapeutics, EarlyView.
The novel application of Virtual Twins (VT) in PBPK (VT‐PBPK) presents the opportunity to advance precision dosing and accelerate the shift from one‐size‐fits‐all to targeted, individualized treatments. This review aims to: (1) critically evaluate existing research on the use of VTs in PBPK, (2) develop a conceptual definition of VT‐PBPK, (3) describe ...
Emily Mannix, Sam Mostafa, Amin Rostami‐Hodjegan, Thomas M. Polasek, Carl M. J. Kirkpatrick   +4 more
wiley   +1 more source

Enoxaparin in Experimental Stroke

, 2001
Background and Purpose —Heparin and heparinoids have long been proposed for stroke treatment. This study investigates the effect of enoxaparin (Lovenox, Clexane), a low-molecular-weight heparin, on functional outcome (neuroscore)
Véronique Mary, Florence Wahl, André Uzan, Jean-Marie Stutzmann   +3 more
core   +1 more source

Rivaroxaban or Enoxaparin in Nonmajor Orthopedic Surgery

, 2020
International audienceBackground: Nonmajor orthopedic surgery of the lower limbs that results in transient reduced mobility places patients at risk for venous thromboembolism.
Duverger, Daniel, Mismetti, Patrick, Mouret, Patrick, Deygas, Béatrice, Laporte, Silvy, Fisher, William, Rosencher, Nadia, Llau, Juan, Presles, Emilie, Martínez-Martín, Javier, Samama, C. Marc, Cucherat, Michel, Girard, Philippe   +12 more
core   +1 more source

Connecting the dots: A narrative review of the relationship between heart failure and cognitive impairment

ESC Heart Failure, Volume 12, Issue 2, Page 1119-1131, April 2025.
Abstract Large clinical data underscore that heart failure is independently associated to an increased risk of negative cognitive outcome and dementia. Emerging evidence suggests that cerebral hypoperfusion, stemming from reduced cardiac output and vascular pathology, may contribute to the largely overlapping vascular dementia and Alzheimer's disease ...
Mauro Massussi, Maria Giulia Bellicini, Marianna Adamo, Andrea Pilotto, Marco Metra, Alessandro Padovani, Riccardo Proietti   +6 more
wiley   +1 more source

Estimated impact of model‐guided venous thromboembolism prophylaxis versus real‐world practice

Journal of Hospital Medicine, EarlyView.
Abstract Background The American Society of Hematology (ASH) recommends assessing venous thromboembolism (VTE) and major bleeding risk to optimize pharmacological VTE prophylaxis for medical inpatients. However, the clinical utility of model‐guided approaches remains unknown.
Benjamin G Mittman, Michael B. Rothberg
wiley   +1 more source

Evaluation of Initial Enoxaparin Dosing and Antifactor Xa Levels in Infants Admitted to the Neonatal Intensive Care Unit

Biomedicine Hub
Introduction: Infants are at risk for thrombotic conditions due to multiple risk factors such as congenital heart defects and sepsis. According to the American College of Chest Physicians (ACCP) 2012 guidelines, enoxaparin may be given for thrombotic ...
Rosemarie Nagy, Trina Hemmelgarn, Stephen Deptola, Brianna Hemmann   +3 more
doaj   +1 more source