Results 71 to 80 of about 4,789 (198)
Characterization of Monoclonal Antibodies to the Plasma Cell Alloantigen ENPP1 [PDF]
The ectonucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) has documented roles in mineralization, nucleotide recycling, and insulin resistance. While ENPP1 was first identified as an alloantigen on mouse plasma cells (PCs), later studies revealed expression in many tissues.
Sadia, Abbasi +9 more
openaire +2 more sources
The Human Ovary Exhibits Dynamic Molecular Remodeling in the Decades Post‐Menopause
We analyzed the proteomes of healthy ovaries from 28 postmenopausal women (50–75 years old). We quantified 5812 proteins and observed progressive age‐associated shifts. This fundamentally shifts the notion of the postmenopausal ovary as an inert organ and demonstrates continuous molecular remodeling with relevance to tissue signaling and implications ...
Mark A. Watson +8 more
wiley +1 more source
Generalized arterial calcification of infancy (GACI) is associated with biallelic mutations in ENPP1 in the majority of cases, whereas mutations in ABCC6 are known to cause pseudoxanthoma elasticum (PXE).
Yvonne eNitschke, Frank eRutsch
doaj +1 more source
Nucleic Acids as Emerging Regulators of Calcium Phosphate Biomineralization
Calcium phosphate biomineralization has traditionally been considered a protein‐regulated process. This review highlights the emerging role of nucleic acids, which interact with mineral phases through adsorption, coprecipitation, and templating, thereby influencing crystal nucleation and growth.
Fanny Duhalde +2 more
wiley +1 more source
Introduction: Several studies regarding the association of the ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) K121Q gene polymorphism with the risk of type 2 diabetes mellitus (T2DM) showed inconsistent results.
Jonny Karunia Fajar
doaj +1 more source
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn +13 more
wiley +1 more source
ATP metabolizing enzymes ENPP1, 2 and 3 are localized in sensory neurons of rat dorsal root ganglion
In dorsal root ganglion (DRG) neurons, ATP is an important neurotransmitter in nociceptive signaling through P2 receptors (P2Rs) such as P2X2/3R, and adenosine is also involved in anti-nociceptive signaling through adenosine A1R.
Kentaro Nishida +4 more
doaj +1 more source
Advances in Immunological Combination Therapy for Colorectal Cancer
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu +7 more
wiley +1 more source
ASQ-3 instrument scores for infants/children with ENPP1 Deficiency/ infant onset ABCC6 Deficiency.
ASQ-3 instrument scores for infants/children with ENPP1 Deficiency/ infant onset ABCC6 Deficiency.
Pedro Huertas (4891903) +5 more
core +1 more source
In silico predictions of ENPP1 variants and comparison with experimental results.
The five previously unreported variants in ENPP1 were italic and underlined.
Amir Hossein Saeidian (12525125) +11 more
core +1 more source

