Results 81 to 90 of about 1,838,152 (282)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Categories enriched over oplax monoidal categories
, 2022 63 pagesWe define a notion of category enriched over an oplax monoidal category $V$, extending the usual definition of category enriched over a monoidal category. Even though oplax monoidal structures involve infinitely many functors $V^n\to V$, defining
Morand, Kevin +2 more
core +1 more source
Weak n-Ary Relational Products in Allegories
Axioms, 2014 Allegories are enriched categories generalizing a category of sets and binary relations. Accordingly, relational products in an allegory can be viewed as a generalization of Cartesian products.
Bartosz Zieliński, Paweł Maślanka
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
BMC GenomicsBackground Genetically modified (GM) crop plants with transgenic expression of Bacillus thuringiensis (Bt) pesticidal proteins are used to manage feeding damage by pest insects.
Yangzhou Wang +5 more
doaj +1 more source
Caspase-3 Cleaves Extracellular Vesicle Proteins During Auditory Brainstem Development
Frontiers in Cellular Neuroscience, 2020 Sound localization requires extremely precise development of auditory brainstem circuits, the molecular mechanisms of which are largely unknown. We previously demonstrated a novel requirement for non-apoptotic activity of the protease caspase-3 in chick ...
Forrest Weghorst +7 more
doaj +1 more source
Enriched model categories and presheaf categories
, 2011 We collect in one place a variety of known and folklore results in enriched model category theory and add a few new twists. The central theme is a general procedure for constructing a Quillen adjunction, often a Quillen equivalence, between a given V-model category and a category of enriched presheaves in V, where V is any good enriching category.
Guillou, Bertrand J., May, J. Peter
openaire +3 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Categories enriched on two sides [PDF]
, 2002 We introduce morphisms V --> W of bicategories, more general than the original ones of Benabou. When V = 1, such a morphism is a category enriched in the bicategory W.
Street, Ross +7 more
core +1 more source
Enriched functor categories for functor calculus [PDF]
, 2022 In this paper we present background results in enriched category theory and enriched model category theory necessary for developing model categories of enriched functors suitable for doing functor calculus.Comment: 37 pages.
Johnson, Brenda +4 more
core +1 more source