Results 131 to 140 of about 1,044,040 (304)

Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions? A systematic review

Frontiers in Cellular Neuroscience
Autophagy is a key regulator of cellular homeostasis and neuronal survival, particularly under adverse physiological conditions. Environmental enrichment (EE), a non-pharmacological intervention providing enhanced sensory, cognitive, and motor ...
Clarice Beatriz Gonçalves Silva, Matheus Santos de Sousa Fernandes, Matheus Santos de Sousa Fernandes, Debora Dantas Nucci Cerqueira, Debora Dantas Nucci Cerqueira, Gabriela Carvalho Jurema Santos, Fatma Hilal Yagin, Yalin Aygun, Georgian Badicu, Fabiana S. Evangelista, Pablo Prieto-González, Fabrício Oliveira Souto, Fabrício Oliveira Souto, Ashit Kumar Dutta, Sameer Badri Al-Mhanna, Sameer Badri Al-Mhanna, Sameer Badri Al-Mhanna, Abedelmalek Kalefh Tabnjh, Abedelmalek Kalefh Tabnjh, Abedelmalek Kalefh Tabnjh   +19 more
doaj   +1 more source

Laboratory evaluation of stable isotope labeling of Culicoides (Diptera: Ceratopogonidae) for adult dispersal studies. [PDF]

, 2019
BackgroundStable isotope labeling is a promising method for use in insect mark-capture and dispersal studies. Culicoides biting midges, which transmit several important animal pathogens, including bluetongue virus (BTV) and epizootic hemorrhagic disease ...
Gerry, Alec C, Hamer, Gabriel L, Maupin, Christopher R, Mayo, Christie E, McDermott, Emily G, Mullens, Bradley A, Roark, E Brendan   +6 more
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

HEP^® (Homeostasis-Enrichment-Plasticity) Approach Changes Sensory–Motor Development Trajectory and Improves Parental Goals: A Single Subject Study of an Infant with Hemiparetic Cerebral Palsy and Twin Anemia Polycythemia Sequence (TAPS)

Children
Background: Early intervention (EI) for infants identified as being at high risk for cerebral palsy (CP), or who have been diagnosed with it, is critical for promotion of postnatal brain organization.
Aymen Balikci, Teresa A. May-Benson, Gamze Cagla Sirma, Gul Ilbay   +3 more
doaj   +1 more source

Supernova enrichment and dynamical histories of solar-type stars in clusters

, 2013
We use N-body simulations of star cluster evolution to explore the hypothesis that short-lived radioactive isotopes found in meteorites, such as 26-Al, were delivered to the Sun's protoplanetary disc from a supernova at the epoch of Solar System ...
Church, Ross P., Davies, Melvyn B., Meyer, Michael R., Parker, Richard J.   +3 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Creating enriched environments for ageing adults

Gerontechnology, 2014
No abstract ...
openaire   +1 more source

A linked data-driven & service-oriented architecture for sharing educational resources [PDF]

, 2011
The two fundamental aims of managing educational resources are to enable resources to be reusable and interoperable and to enable Web-scale sharing of resources across learning communities.
Dietze, Stefan, Domingue, John, Dovrolls, Nikolas, Kaldoudi, Eleni, Li, Ning, Pedrinaci, Carlos, Stefanut, Teodor, Taibi, Davide, Yu, Hong Qing   +8 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source