Results 141 to 150 of about 7,106,216 (352)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Astroglial Activation by an Enriched Environment after Transplantation of Mesenchymal Stem Cells Enhances Angiogenesis after Hypoxic-Ischemic Brain Injury

International Journal of Molecular Sciences, 2016
Transplantation of mesenchymal stem cells (MSCs) has paracrine effects; however, the effects are known to be largely limited. Here we investigated the combination effects of cell transplantation and enriched environment (EE) in a model of hypoxic ...
Sung-Rae Cho, H. Suh, Ji Hea Yu, H. Kim, J. Seo, C. Seo   +5 more
semanticscholar   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Editorial: The Effects of Enriched Environment on NK cells and Macrophages and Their Underlying Mechanisms

Frontiers in Immunology, 2022
Yoshiro Kobayashi, Cristina Limatola, Cristina Limatola, Yu Gan   +3 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Chemical evolution in star clusters: the role of mass and environment [PDF]

arXiv, 2013
The process of chemical self-enrichment in stellar systems can be affected by the total mass of the system and the conditions of the large-scale environment. Globular clusters are a special dark matter-free case of chemical evolution, in which the only self-enrichment comes from material processed in stars, and only two bursts of star formation occur ...
arxiv  

EFFECTS OF GIBBERELLIC ACID ON GROWTH OF ANTIRRHINUM MAJUS ’UTAH WHITE’ IN A CARBON DIOXIDE-ENRICHED ENVIRONMENT [PDF]

, 1968
Te-sen Pih, E. W. Toop
openalex   +1 more source

Qualitative investigation of the perceptions and experiences of nursing and allied health professionals involved in the implementation of an enriched environment in an Australian acute stroke unit

BMJ Open, 2017
Objective An enriched environment embedded in an acute stroke unit can increase activity levels of patients who had stroke, with changes sustained 6 months post-implementation.
I. Rosbergen, S. Brauer, S. Fitzhenry, R. Grimley, K. Hayward   +4 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Effects and mechanisms of different exogenous organic matters on selenium and cadmium uptake by rice in natural selenium-cadmium-rich soil

Heliyon
Many natural selenium (Se)-rich rice plants are being polluted by cadmium (Cd). In this study, for reducing Cd concentrations in rice grains while maintaining Se concentrations, the effects of different exogenous organic matters (OMs), such as humic acid
Hongyu Zhang, Shuyun Xie, Xiaoping Du, Zhengyu Bao, Feng Xu, Salah Fadlallah Awadelseid, Oraphan Yaisamut   +6 more
doaj