Results 161 to 170 of about 7,106,216 (352)

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

open access: yesFEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo   +6 more
wiley   +1 more source

Algorithmic Trading with Fitted Q Iteration and Heston Model [PDF]

open access: yesarXiv, 2018
We present the use of the fitted Q iteration in algorithmic trading. We show that the fitted Q iteration helps alleviate the dimension problem that the basic Q-learning algorithm faces in application to trading. Furthermore, we introduce a procedure including model fitting and data simulation to enrich training data as the lack of data is often a ...
arxiv  

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

open access: yesFEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns   +2 more
wiley   +1 more source

Leaf senescence of Quercus myrtifolia as affected by long‐term CO2 enrichment in its native environment [PDF]

open access: bronze, 2000
J.-H. Li   +6 more
openalex   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

A representational framework for learning and encoding structurally enriched trajectories in complex agent environments [PDF]

open access: yesarXiv
The ability of artificial intelligence agents to make optimal decisions and generalise them to different domains and tasks is compromised in complex scenarios. One way to address this issue has focused on learning efficient representations of the world and on how the actions of agents affect them, such as disentangled representations that exploit ...
arxiv  

The Role of Tenascin-C on the Structural Plasticity of Perineuronal Nets and Synaptic Expression in the Hippocampus of Male Mice

open access: yesBiomolecules
Neuronal plasticity is a crucial mechanism for an adapting nervous system to change. It is shown to be regulated by perineuronal nets (PNNs), the condensed forms of the extracellular matrix (ECM) around neuronal bodies.
Ana Jakovljević   +6 more
doaj   +1 more source

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