Results 61 to 70 of about 996,291 (283)

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

A deep Chandra observation of the poor cluster AWM4 - II. The role of the radio jets in enriching the intra-cluster medium

, 2010
We use a Chandra observation of the poor cluster AWM4 to map the temperature and abundance of the intra-cluster medium, so as to examine the influence of the central radio galaxy on its environment.
Ascasibar, Bildfell, Brüggen, Burns, Böhringer, Cappellaro, Ciotti, David, De Grandi, Denicoló, Edge, Ewan O’Sullivan, Gastaldello, Giacintucci, Gitti, Grevesse, Hicks, Jan M. Vrtilek, Kaastra, Kalberla, Kirkpatrick, Koranyi, Kuntz, Laurence P. David, Markevitch, Mazzotta, McNamara, Mittal, Nomoto, Nulsen, O’Dea, O’Sullivan, O’Sullivan, O’Sullivan, Peterson, Pipino, Rasia, Rasmussen, Rasmussen, Rebusco, Rebusco, Roediger, Salomé, Sanders, Schombert, Simionescu, Simionescu, Simionescu, Simona Giacintucci, Snowden, Somak Raychaudhury, Vikhlinin, Weisskopf, Werner, Xiang   +54 more
core   +1 more source

BIM semantic-enrichment for built heritage representation [PDF]

, 2018
In the built heritage context, BIM has shown difficulties in representing and managing the large and complex knowledge related to non-geometrical aspects of the heritage.
Acierno, Marta, Cursi, Stefano, Simeone, Davide   +2 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

The impact of constitutive mTORC1 hyperactivity on structural synaptic plasticity and social behaviour under standard conditions and environmental enrichment

European Psychiatry, 2022
Introduction Autism spectrum disorders (ASD) are a group of neurodevelopmental disabilities causing major social, communication, and behavioural challenges.
S. Granak, K. Tuckova, V. Kutna, I. Vojtechova, L. Bajkova, T. Petrasek, S. Ovsepian   +6 more
doaj   +1 more source

Latent regulatory potential of human-specific repetitive elements [PDF]

, 2013
At least half of the human genome is derived from repetitive elements, which are often lineage specific and silenced by a variety of genetic and epigenetic mechanisms. Using a transchromosomic mouse strain that transmits an almost complete single copy of
Barbosa-Morais, Nuno L., Blencowe, Benjamin J., Flicek, Paul, Kirschner, Kristina, Kutter, Claudia, Lukk, Margus, Menon, Suraj, Odom, Duncan T., Pan, Qun, Schmidt, Dominic, Schwalie, Petra C., Stark, Rory, Thybert, David, Ward, Michelle C., Watt, Stephen, Wilson, Michael D.   +15 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Perinatal protein malnutrition results in genome-wide disruptions of 5-hydroxymethylcytosine at regions that can be restored to control levels by an enriched environment

Epigenetics, 2021
Maternal malnutrition remains one of the major adversities affecting brain development and long-term mental health outcomes, increasing the risk to develop anxiety and depressive disorders.
Carolina D. Alberca, Ligia A. Papale, Andy Madrid, Octavio Gianatiempo, Eduardo T. Cánepa, Reid S. Alisch, Mariela Chertoff   +6 more
doaj   +1 more source

DiVM: Model Checking with LLVM and Graph Memory

, 2017
In this paper, we introduce the concept of a virtual machine with graph-organised memory as a versatile backend for both explicit-state and abstraction-driven verification of software. Our virtual machine uses the LLVM IR as its instruction set, enriched
Barnat, Jiří, Ročkai, Petr, černá, Ivana, Štill, Vladimír   +3 more
core   +1 more source

Extensive horizontal gene transfer in cheese-associated bacteria. [PDF]

, 2017
Acquisition of genes through horizontal gene transfer (HGT) allows microbes to rapidly gain new capabilities and adapt to new or changing environments.
Bonham, Kevin S, Dutton, Rachel J, Wolfe, Benjamin E   +2 more
core   +3 more sources