Results 61 to 70 of about 1,044,040 (304)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Human Vaccines & Immunotherapeutics, 2018 Objective: To study the effect of enriched environment (EE) on cognitive function and pathological changes in Alzheimer's disease (AD) mice. Method: 6-month-old of the male mice were divided into 3 groups (n = 8), the wild type C57BL/6 mice in the ...
Yuwei Zhang +5 more
doaj +1 more source
Frontiers in Neuroscience, 2019 Xiaoshuan enteric-coated capsule (XSEC) is a Chinese medicinal compound widely used for treatment of ischemic cerebrovascular diseases. Enriched environment (EE) is an effective rehabilitative protocol designed to enhance sensorimotor, cognitive and ...
Yu Zhan +14 more
doaj +1 more source
Enriched Fell Bundles and Spaceoids [PDF]
, 2011 We propose a definition of involutive categorical bundle (Fell bundle) enriched in an involutive monoidal category and we argue that such a structure is a possible suitable environment for the formalization of different equivalent versions of spectral ...
Bertozzini, Paolo +2 more
core
Recovery from population III supernova explosions and the onset of second generation star formation
, 2014 We use cosmological simulations to assess how the explosion of the first stars in supernovae (SNe) influences early cosmic history. Specifically, we investigate the impact by SNe on the host systems for Population~III (Pop~III) star formation and explore
Bromm, Volker +3 more
core +1 more source
Evidence that natural selection maintains genetic variation for sleep in Drosophila melanogaster. [PDF]
, 2015 BackgroundDrosophila melanogaster often shows correlations between latitude and phenotypic or genetic variation on different continents, which suggests local adaptation with respect to a heterogeneous environment.
Begun, David J +4 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in Aging Neuroscience, 2010 Aging is associated with a progressive decline of mental and physical abilities. Considering the current demographic changes in many civilizations there is an urgent need for measures permitting an independent lifestyle into old age. The critical role of
Jan-Christoph Kattenstroth +4 more
doaj +1 more source
ENRICHING WSN ENVIRONMENT WITH CONTEXT INFORMATION
Computer Science, 2012 Currently the Internet of Things environment suffer from a variety of uniqueproblems such as low throughput, inadequate support for mobility and notcompatible(and often close) application environments. However, characteristicof physical environment often provides opportunities to address these problems.This paper explores concepts of enriching the WNS ...
openaire +3 more sources
Pre-reproductive parental enriching experiences influence progeny’s developmental trajectories [PDF]
, 2018 While the positive effects of environmental enrichment (EE) applied after weaning, in adulthood, during aging, or even in the presence of brain damage have been widely described, the transgenerational effects of pre-reproductive EE have been less ...
Berretta, Erica +5 more
core +1 more source