Results 61 to 70 of about 1,344,829 (308)
Discussion on the uniformity of shale oil and gas in China
Shiyou shiyan dizhiShale oil and gas are important strategic resources in China's energy sector, existing in shale formations with self-generation and self-storage characteristics.
Xusheng GUO +5 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
joelbader/regulon-enrichment: First Release
, 2017 <p>This is the first release of our code supporting our manuscript: "Gene enrichment analysis reveals major regulators of <em>Mycobacterium tuberculosis</em> gene expression in two models of antibiotic tolerance".</p ...
Will Matern, Will Matern (8260089)
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
, 2021 Gene function enrichment analysis: GO function enrichment analysis (A) and KEGG pathway enrichment analysis (B).
Yuxiang Liu (290490) +7 more
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Thirty years later: Enrichment practices for captive mammals
, 2009 Environmental enrichment of captive mammals has been steadily evolving over the past thirty years. For this process to continue, it is first necessary to define current enrichment practices and then identify the factors that limit enhancing the quality ...
Peter J. Murray +5 more
core +1 more source
Shiyou shiyan dizhiContinental shale oil and gas are important areas for increasing oil and gas reserves and production in China. However, traditional macroscopic-to-core scale studies are insufficient to reveal the relationship between material migration within laminae ...
Jianbin TENG +7 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2012 The provision of environmental enrichment to mice used in research is a topic that generates often widely divergent opinions as to the value of this husbandry practice. The literature is replete with examples of the positive effects enrichment has on the
Bayne, Kathryn +3 more
core +1 more source