Results 61 to 70 of about 1,292,580 (305)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Regulation mechanisms of material transfer within continental shale on reservoir properties: a case study of shale from upper submember of fourth member of Paleogene Shahejie Formation, Niuzhuang Subsag, Bohai Bay Basin

open access: yesShiyou shiyan dizhi
Continental shale oil and gas are important areas for increasing oil and gas reserves and production in China. However, traditional macroscopic-to-core scale studies are insufficient to reveal the relationship between material migration within laminae ...
Jianbin TENG   +7 more
doaj   +1 more source

Numerical Simulation on Hydrofracture Propagation in Fractured-Vuggy Unconventional Reservoirs

open access: yesGeofluids, 2022
The unconventional reservoirs such as carbonate formation develops complex and diverse storage space structures, and it is composed of large-scale cavity, dissolved vug, and fractures. The carbonate reservoir is highly heterogeneous.
Tingxue Jiang   +5 more
doaj   +1 more source

Enriched Interpretation

open access: yesCoRR, 2018
10 pages, Conference Proceedings of the Third International Workshop on Rough Sets and Soft Computing (RSSC'94), T.Y.
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Free atmospheric CO2 enrichment increased above ground biomass but did not affect symbiotic N2-fixation and soil carbon dynamics in a mixed deciduous stand in Wales [PDF]

open access: yes, 2011
Through increases in net primary production (NPP), elevated CO2 is hypothesizes to increase the amount of plant litter entering the soil. The fate of this extra carbon on the forest floor or in mineral soil is currently not clear.
A. R. Smith   +14 more
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Laboratory experimental research on production characteristics with CO2 injection in shale oil

open access: yesShiyou shiyan dizhi
Depletion development of shale oil reservoirs after fracturing tends to face challenges including rapid production decline, rapid formation energy attenuation, and low recovery efficiency.
Maolei CUI   +7 more
doaj   +1 more source

Pre-stack seismic density inversion in marine shale reservoirs in the southern Jiaoshiba area, Sichuan Basin, China

open access: yesPetroleum Science, 2018
For a typical marine shale reservoir in the Jiaoshiba area, Sichuan Basin of China, P-impedance is sensitive for identifying lithology but not suitable for indicating good shale reservoirs.
Yuan-Yin Zhang   +5 more
doaj   +1 more source

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