Results 51 to 60 of about 1,168,064 (316)

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

Bi-directional gene set enrichment and canonical correlation analysis identify key diet-sensitive pathways and biomarkers of metabolic syndrome. [PDF]

, 2010
peer-reviewedBackground Currently, a number of bioinformatics methods are available to generate appropriate lists of genes from a microarray experiment.
Morine Melissa J, Aidan P Moloney, Toomey Sinead, Melissa J Morine, McMonagle, Jolene, Roche, Helen M., Gaora Peadar Ó, Moloney, Aidan P, Isobel C Gormley, Helen M Roche, O Gaora, Peadar, Peadar Ó Gaora, Roche Helen M, Moloney Aidan P, Reynolds Clare M, Sinead Toomey, Toomey, Sinead, Jolene McMonagle, Clare M Reynolds, Morine, Melissa J, McMonagle Jolene, Gormley, Isobel C, Gormley Isobel C, Reynolds, Clare M   +23 more
core   +1 more source

Volume fracturing of deep shale gas horizontal wells

Natural Gas Industry B, 2017
Deep shale gas reservoirs buried underground with depth being more than 3500 m are characterized by high in-situ stress, large horizontal stress difference, complex distribution of bedding and natural cracks, and strong rock plasticity.
Tingxue Jiang, Xiaobing Bian, Haitao Wang, Shuangming Li, Changgui Jia, Honglei Liu, Haicheng Sun   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Elastic Reverse Time Migration for Weakly Illuminated Structure

Applied Sciences, 2022
One of the most effective techniques to obtain PP and PS images is elastic reverse time migration which employs multi-component seismic data. The two types of complementary images play an important role in reducing blind spots in seismic exploration ...
Liwei Song, Ying Shi, Wei Liu, Qiang Zhao   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The Scent Enriched Primate

Animals, 2023
Zoos worldwide play an important role in both in situ and ex situ conservation via efforts such as providing breeding programmes and reintroductions into the wild. Zoo populations are crucial as a buffer against extinction. However, a mismatch between the wild and zoo environments can lead to psychological as well as physiological health issues, such ...
Emily J. Elwell, Stefano Vaglio
openaire   +5 more sources

Mouse enrichment [PDF]

, 2012
The provision of environmental enrichment to mice used in research is a topic that generates often widely divergent opinions as to the value of this husbandry practice. The literature is replete with examples of the positive effects enrichment has on the
Bayne, Kathryn, Kathryn Bayne, Würbel, Hanno, Hanno Würbel   +3 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Paradox of Enrichment in Metaecosystems [PDF]

The American Naturalist, 2014
The paradox of enrichment has been studied almost exclusively within communities or metacommunities, without explicit nutrient dynamics. Yet local recycling of materials from enriched ecosystems may affect the stability of connected ecosystems. Here we study the effect of nutrient, detritus, producer, and consumer spatial flows-combined with changes in
Gounand, Isabelle, Mouquet, Nicolas, Canard, Elsa, Guichard, Frederic, Hauzy, Céline, Gravel, Dominique   +5 more
openaire   +5 more sources