Results 41 to 50 of about 14,747,636 (304)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
MBE: model-based enrichment estimation and prediction for differential sequencing data
Characterizing differences in sequences between two conditions, such as with and without drug exposure, using high-throughput sequencing data is a prevalent problem involving quantifying changes in sequence abundances, and predicting such differences for
Akosua Busia, Jennifer Listgarten
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The laminae of lacustrine shale in China have been systematically identified and characterized by a combination of core/slice observations, mineral compositions, geochemical analysis, pore structure characterization, and oil-bearing evaluation. The shale
Mengying Li +8 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Single-image to model registration for semantic enrichment of indoor BIM [PDF]
Effective integration of geometric and semantic data within Building Information Models (BIM) is essential for the efficient life cycle management of modern facilities.
D. Włodarczyk, M. Jarząbek-Rychard
doaj +1 more source
Models of helium enrichment in helium-rich gas reservoirs of petroliferous basins in China
Owing to the characteristics of chemical inertness, low molecular weight, low boiling point, strong permeability and high heat conductivity, helium is extensively used in the fields of aerospace, low-temperature superconductivity, medicine and high tech,
Shengfei Qin +4 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Operant Methodology Out Of The Lab and Applied To Enrichment With Captive Chimpanzees (Pan Troglodytes) [PDF]
A group of socially-housed chimpanzees, maintained in a zoo facility, were given the opportunity to access each of several purpose-designed and built enrichment items.
Vivian, Melanie
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