Results 91 to 100 of about 331,611 (314)

Draft Genome Sequence of Multidrug-Resistant Abortive Campylobacter jejuni from Northern California. [PDF]

, 2017
Campylobacter jejuni is an enteric bacterium that can cause abortion in livestock. This is the release of a multidrug-resistant Campylobacter jejuni genome from an isolate that caused an abortion in a cow in northern California.
Clothier, Kristin A, Huang, Bihua C, Kong, Nguyet, Weimer, Bart C, Weis, Allison M   +4 more
core   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic MiceSummary

Cellular and Molecular Gastroenterology and Hepatology, 2016
Background & Aims: Gastroparesis is a complication of diabetes characterized by delayed emptying of stomach contents and accompanied by early satiety, nausea, vomiting, and pain. No safe and reliable treatments are available.
Kyoung Moo Choi, Simon J. Gibbons, Lei Sha, Arthur Beyder, Pieter-Jan Verhulst, Gianluca Cipriani, Jessica E. Phillips, Anthony J. Bauer, Tamas Ordog, Jon J. Camp, Xin Ge, Adil E. Bharucha, David R. Linden, Joseph H. Szurszewski, Purna C. Kashyap, Gianrico Farrugia   +15 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Assembly, Biochemical Characterization, Immunogenicity, Adjuvanticity, and Efficacy of Shigella Artificial Invaplex

mSphere, 2018
The native Invaplex (InvaplexNAT) vaccine and adjuvant is an ion exchange-purified product derived from the water extract of virulent Shigella species.
K. Ross Turbyfill, Kristen A. Clarkson, Anthony R. Vortherms, Edwin V. Oaks, Robert W. Kaminski   +4 more
doaj   +1 more source

Effect of probiotic inocula on the population density of lactic acid bacteria and enteric pathogens in the intestine of weaning piglets [PDF]

, 2007
Because antibiotic resistance occurs in bacteria at an alarming rate, significant research has been focused on finding alternative treatments which do not involve the use of antibiotics.
Biavati, Bruno, Bosi, Paolo, D'Aimmo, Maria Rosaria, Mazzoni, Maurizio, Modesto, Monica, Stefanini, Ilaria, Tittarelli, Carla, Trevisi, Paolo   +7 more
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Incidence of diarrhea caused by rotavirus infections in rural Zhengding, China: prospective, population-based surveillance.

, 2005
Rotavirus is the pathogen most commonly associated with severe gastroenteritis in young children in the People's Republic of China, yet there are few population-based data on the incidence of rotavirus infection. The present study investigated the burden
Wang, Xuan-Yi, Xu, Zhi-Yi, von Seidlein, Lorenz, Zhang, Ying-Lin, Zhao, Shou-Jun, Hao, Zhi-Yong, Han, Oak Pil, Kilgore, Paul, Xing, Zhan-Chun, Han, Chang-Quan, Ma, Jing-Chen, Chen, Ji-Chao, Clemens, John   +12 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The malaria and typhoid fever burden in the slums of Kolkata, India: data from a prospective community-based study.

, 2006
Recent research has indicated that the malaria burden in Asia may have been vastly underestimated. We conducted a prospective community-based study in an impoverished urban site in Kolkata, India, to estimate the burden of malaria and typhoid fever and ...
Acosta, Camilo J, Ali, Mohammad, Bhattacharya, Sujit K, Clemens, John D, Deb, Alok K, Deen, Jacqueline L, Dutta, Shanta, Gupta, Vinay Kumar, Kanungo, Suman, Kim, Deok Ryun, Manna, Byomkesh, Ochiai, R Leon, Sarkar, Banwari Lal, Sur, Dipika, Tsuzuki, Ataru, von Seidlein, Lorenz   +15 more
core   +1 more source