Results 81 to 90 of about 213,242 (313)

OBESITY AND ENTERIC NERVOUS SYSTEM MODULATION: EVIDENCE FROM PRECLINICAL ANIMAL MODELS

open access: yes, 2022
Nutrient absorption and energy metabolism are regulated by the enteric nervous system (ENS), which thereby controls the onset of obesity. In addition, the interplay between obesity and cognitive dysfunction via the gut-brain axis has been reported ...
Tayebati SK   +7 more
core  

Enteric Neural Stem Cell Therapies for Enteric Neuropathies [PDF]

open access: yes, 2018
BACKGROUND: Enteric neuropathies exist as a wide range of human disorders which impact on gastrointestinal motility. Current standard therapies for enteric neuropathies are limited to surgical resection or manipulation (eg, myotomy) of affected gut ...
N. Thapar   +3 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Vibrio fluvialis: An Emerging Pathogen

open access: yesFrontiers in Microbiology, 2014
Vibrio fluvialis is a pathogen commonly found in costal environs. Considering recent increase in numbers of diarrheal outbreaks and sporadic extraintestinal cases, V. fluvialis has been considered as an emerging pathogen.
Thandavarayan eRamamurthy   +3 more
doaj   +1 more source

The potential role of Rac signalling and the planar cell polarity pathway in wiring of the enteric nervous system

open access: yes, 2011
The functional development of the enteric nervous system (ENS) requires newly generated neurons and their progenitors to migrate to their appropriate sites, extend neurites, guide axons and dendrites to suitable locations and establish synaptic ...
Sasselli, V.
core  

Enteric glial cells: New players in Parkinson's disease?

open access: yes, 2015
International audienceLewy pathology has been described in neurons of the enteric nervous system in nearly all Parkinson's disease (PD) patients at autopsy.
Thomas Clairembault   +7 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Enteric Viruses Co-infection with Giardiasis among Diarrheal Children in Diyala Province - Iraq

open access: yes, 2018
Mixed infections of enteric viruses and parasite can infected the human alimentary canal and quite complex physiological changes can result from such infection.
Mohammed Jasim Shaker   +2 more
core   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

Assembly, Biochemical Characterization, Immunogenicity, Adjuvanticity, and Efficacy of Shigella Artificial Invaplex

open access: yesmSphere, 2018
The native Invaplex (InvaplexNAT) vaccine and adjuvant is an ion exchange-purified product derived from the water extract of virulent Shigella species.
K. Ross Turbyfill   +4 more
doaj   +1 more source

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