Results 71 to 80 of about 331,611 (314)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

The Nav1.9 channel regulates colonic motility in mice

Frontiers in Neuroscience, 2013
The colonic migrating motor complex (CMMC) is a major pattern of motility that is entirely generated and organized by the enteric nervous system (ENS). We have previously demonstrated that the Nav1.9 channel underlies a tetrodotoxin-resistant Na+ current
Carine eCopel, Nadine eClerc, Nancy eOsorio, Patrick eDelmas, Bruno eMazet   +4 more
doaj   +1 more source

Enteric diseases in pigs from weaning to slaughter [PDF]

, 2003
The general aim of this thesis was to study enteric diseases in growing pigs, with special reference to diseases caused by Brachyspira hyodysenteriae and Lawsonia intracellularis. The occurrence of enteric diseases in “growers” is a problem of increasing
Jacobson, Magdalena
core  

Mass administrations of antimalarial drugs.

, 2003
Administration of antimalarial drugs to whole populations has been used as a malaria-control measure for more than 70 years. Drugs have been administered either directly as a full therapeutic course of treatment or indirectly through the fortification of
Greenwood, Brian M, von Seidlein, Lorenz
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Fabrication and mechanical testing of polydioxanone hook cross biodegradable self-expandable enteric stent: impact of fabrication density and mechanical properties of the stent [PDF]

Clinical Endoscopy
Background/Aims The mechanical properties of biodegradable stent when fabricated using different number of pins per row of fabrication has been limited. We compared the radial compressive force of polydioxanone (PDO) stent that was fabricated in hook and
Tanyaporn Chantarojanasiri, Juthamas Ratanavaraporn, Saran Keeratihattayakorn   +2 more
doaj   +1 more source

Controlling the bacterial load of Salmonella Typhi in an experimental mouse model by a lytic Salmonella phage STWB21: a phage therapy approach

BMC Microbiology, 2023
Background Salmonella enterica serotype Typhi is one of the major pathogens causing typhoid fever and a public health burden worldwide. Recently, the increasing number of multidrug-resistant strains of Salmonella spp.
Payel Mondal, Prolay Halder, Bani Mallick, Subhadip Bhaumik, Hemanta Koley, Shanta Dutta, Moumita Dutta   +6 more
doaj   +1 more source

Vital dye labelling demonstrates a sacral neural crest contribution to the enteric nervous system of chick and mouse embryos [PDF]

, 1991
We have used the vital dye, DiI, to analyze the contribution of sacral neural crest cells to the enteric nervous system in chick and mouse embryos. In order to label premigratory sacral neural crest cells selectively, DiI was injected into the lumen of ...
Bronner-Fraser, Marianne, Burgan, Scott, Fraser, Scott E., Serbedzija, George N.   +3 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Enteric thymic adenocarcinoma: Understanding a unique pathology in the mediastinum

Indian Journal of Pathology and Microbiology
Thymic malignancies are rare neoplasms, with thymoma and thymic carcinoma—collectively known as thymic epithelial tumors (TETs)—being uncommon tumors that originate from the thymus.
Raja Chhabra, Kartik Mittal, Anmol Tufchi, Sajjan Rajpurohit, Deepak Kumar Mittal, Aditya Vidushi, Swati Saxena, Md Ali Osama   +7 more
doaj   +1 more source