Results 241 to 250 of about 281,954 (293)

1,2‐propanediol reformulation improves tribromoethanol safety and reveals pontine GABRA1 enrichment as a candidate mechanistic correlate of anesthesia

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study develops a reformulated tribromoethanol (TBE) anesthetic using 1,2‐propanediol as a solvent to overcome solvent‐related toxicity. The novel formulation demonstrates, cardiovascular stability, and survival in prolonged protocols. It provides potent, dose‐dependent anesthesia without strain or sex differences.
Xia Li   +3 more
wiley   +1 more source

Molecular Details of RNA Interactions With FUS Condensates Altering Assembly, Dynamics, and Aggregation

open access: yesAngewandte Chemie, EarlyView.
Using NMR and molecular simulations, we map how RNA engages FUS LC‐RGG1 within condensates through electrostatic, π‐stacking, and polar contacts. These multivalent RNA contacts help stabilize RNA within FUS condensates while also reshaping condensate composition and dynamics.
Tongyin Zheng   +6 more
wiley   +1 more source

Radical, Not Ionic: The Mechanochemical Zincke Nitration of Phenols

open access: yesAngewandte Chemie, EarlyView.
Mechanochemistry recasts the classical Zincke nitration as an open‐shell process. Liquid‐assisted vibrational milling of phenols with in situ HNO2 delivers direct and ipso nitration across 50 substrates, while atmosphere, NOx‐transfer, EPR and DFT evidence expose a phenoxyl‐radical/NO2 manifold underlying this historically ionic transformation ...
Roberto Scipione   +7 more
wiley   +1 more source

Proanthocyanidins inhibit methane emissions by interacting with methyl-coenzyme M reductase and reshaping rumen microbiome function. [PDF]

open access: yesMicrobiome
Liu Z   +16 more
europepmc   +1 more source

Methane mitigation, nutritional evaluation, and in vitro degradation kinetics of diets based on tropical grass haylage treated with xylanase. [PDF]

open access: yesTrop Anim Health Prod
Duarte ABA   +12 more
europepmc   +1 more source

Methane emissions in beef cattle: A review of measurements and mitigation strategies. [PDF]

open access: yesVet Anim Sci
Taiwo E   +4 more
europepmc   +1 more source

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