Results 221 to 230 of about 17,304,241 (289)

Disease-specific alterations of the enteric nervous system in precancerous colonic mucosa and their implications for mucin regulation. [PDF]

Sci Rep
Imura T, Miyagawa-Hayashino A, Honda M, Harusato A, Katada K, Konishi E.   +5 more
europepmc   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

The enteric nervous system is 10 times stiffer than the brain. [PDF]

Biophys J
Chevalier NR, Peaucelle A, Guilbert T, Bourdoncle P, Xi W.   +4 more
europepmc   +1 more source

Large‐scale Whole‐Exome Sequencing Defines the Protein‐Coding Architecture of Retinal Structure, Visual Function, and Major Blinding Diseases

Advanced Science, EarlyView.
Large‐scale whole‐exome sequencing in 356,982 UK Biobank participants defines the protein‐coding architecture of retinal structure, visual function, and major blinding diseases. Pleiotropic genes, including CFI, C3, and RIOX1, bridge multiple retinal phenotypes, while experimental validation of FYB2 implicates RPE barrier dysfunction, providing ...
Jianqing Li, Yijun Ge, Jingxiao Du, Liu Yang, Bangsheng Wu, Chenyue Hang, Mengxi Shen, Yimin Mao, Ting Zhang, Qiyu Bo, Tianyuan Zhao, Yutian Jiao, Yazhi Wang, Shunxiang Gao, Jieqiong Chen, Junran Sun, Tong Li, Huixun Jia, Yang Dou, Wei Cheng, Xiaoling Wan, Jintai Yu, Xiaodong Sun, Bai Lu   +23 more
wiley   +1 more source

The role of the enteric nervous system in the pathogenesis of Clostridioides difficile infection. [PDF]

Nat Rev Gastroenterol Hepatol
Costa DVS, Thomasi B, Brito GAC, Gulbransen BD, Warren CA.   +4 more
europepmc   +1 more source

Apoptosis in the enteric nervous system: effects evoked by anti-HuD antibody in cultured myenteric neurons

, 2003
BOVARA M, TONINI, MARCELLO, BARBARA G, SARNELLI G, CORINALDESI R, STANGHELLINI V, DE PONTI, FABRIZIO, DE GIORGIO R., CERVIO, ELISABETTA, CUOMO R, GUERRINI S, KOUMANDOU M   +11 more
core  

Polydopamine Nanoparticle‐Mediated Precise Near‐Infrared Optical Stimulation for Cognitive Enhancement

Advanced Science, EarlyView.
Polydopamine nanoparticles enable a precise, non‐genetic, and transcranial neuromodulation strategy via near‐infrared photothermal stimulation. By activating TRPV1 channels, this approach specifically enhances hippocampal gamma oscillations, thereby rescuing spatial memory deficits in models of perioperative neurocognitive disorder.
Yan‐Bo Zhou, Qiong Xue, Su‐Xuan Hou, Ke‐Yao Zhang, Wei‐Tong Pan, Ting‐Ting Zeng, Yu‐Ge Wang, Daqing Ma, Chenguang Zhao, Pan‐Miao Liu, Jian‐Jun Yang   +10 more
wiley   +1 more source

Whole-Gut Spatial Genomic Analysis Reveals Molecular Regionalization of the Differentiating Zebrafish Enteric Nervous System. [PDF]

FASEB J
Moreno-Campos R, Mummaneni NS, Uribe RA.
europepmc   +1 more source

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Stereoscopic Quantitative Analysis of Enteric Nervous System in Patients With Slow Transit Constipation. [PDF]

Neurogastroenterol Motil
Tian G, Wang B, Kong B, Yuan Z, Yang Y, Wang Z, Liu D, Zhao S.   +7 more
europepmc   +1 more source