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The enteric nervous system and neurogastroenterology
Nature Reviews Gastroenterology and Hepatology, 2012 Neurogastroenterology is defined as neurology of the gastrointestinal tract, liver, gallbladder and pancreas and encompasses control of digestion through the enteric nervous system (ENS), the central nervous system (CNS) and integrative centers in sympathetic ganglia.
J B Furness, Furness John B
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Current Opinion in Gastroenterology, 2005 The purpose of this review is to provide a synopsis of how the field of enteric neurobiology has advanced during the past 2 years.With more than 500 studies from which to choose, the authors have focused on several themes that illustrate recent progress.
David, Grundy, Michael, Schemann
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Physiological Reviews, 2023
Of all the organ systems in the body, the gastrointestinal tract is the most complicated in terms of the numbers of structures involved, each with different functions, and the numbers and types of signaling molecules utilized. The digestion of food and absorption of nutrients, electrolytes, and water occurs in a hostile luminal environment that ...
Keith A Sharkey, Gary M Mawe
exaly +3 more sources
Of all the organ systems in the body, the gastrointestinal tract is the most complicated in terms of the numbers of structures involved, each with different functions, and the numbers and types of signaling molecules utilized. The digestion of food and absorption of nutrients, electrolytes, and water occurs in a hostile luminal environment that ...
Keith A Sharkey, Gary M Mawe
exaly +3 more sources
The enteric nervous system: the hub in a star network
Nature Reviews Gastroenterology and Hepatology, 2020The enteric nervous system (ENS) is an important component of gastrointestinal function and a pivotal hub connecting the gut to other organs. A new study now explores the human and mouse ENS at the single-cell level, providing key insights into the transcriptomic landscape of the ENS and its constituent cells.
Ana Carina Bon-Frauches +2 more
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CART in the enteric nervous system
Peptides, 2006 The expression, distribution, origin, projections, chemical coding and functions of cocaine and amphetamine-regulated transcript (CART) in the gastro-intestinal tract are reviewed. CART is extensively expressed in the enteric nervous system. Except from being a possible modulator of NO induced intestinal relaxation CART does not seem to play any ...
Lund University., Ekblad, Eva,
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New England Journal of Medicine, 1996
The enteric nervous system is a collection of neurons in the gastrointestinal tract1 that constitutes the “brain of the gut” and can function independently of the central nervous system.2 This system controls the motility,3,4 exocrine and endocrine secretions,5 and microcirculation6 of the gastrointestinal tract; it is also involved in regulating ...
R K, Goyal, I, Hirano
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The enteric nervous system is a collection of neurons in the gastrointestinal tract1 that constitutes the “brain of the gut” and can function independently of the central nervous system.2 This system controls the motility,3,4 exocrine and endocrine secretions,5 and microcirculation6 of the gastrointestinal tract; it is also involved in regulating ...
R K, Goyal, I, Hirano
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Overview of the Enteric Nervous System
Seminars in Neurology, 2023AbstractPropulsion of contents in the gastrointestinal tract requires coordinated functions of the extrinsic nerves to the gut from the brain and spinal cord, as well as the neuromuscular apparatus within the gut. The latter includes excitatory and inhibitory neurons, pacemaker cells such as the interstitial cells of Cajal and fibroblast-like cells ...
Gary M, Mawe +2 more
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Proceedings of the National Academy of Sciences of the United States of America, 2018 The enteric nervous system (ENS) is crucial for essential gastrointestinal physiologic functions such as motility, fluid secretion, and blood flow. The gut is colonized by trillions of bacteria that regulate host production of several signaling molecules
Filipe De Vadder +2 more
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Plasticity in the enteric nervous system
Gastroenterology, 1999Enteric ganglia can maintain integrated functions, such as the peristaltic reflex, in the absence of input from the central nervous system, which has a modulatory role. Several clinical and experimental observations suggest that homeostatic control of gut function in a changing environment may be achieved through adaptive changes occurring in the ...
GIARONI, CRISTINA +4 more
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Monoamines in the enteric nervous system
Histochemistry and Cell Biology, 2018Recent advances in neurogastroenterology have extended and refined our knowledge on the roles monoamines play in physiology and pathophysiology of the gastrointestinal tract. The catecholamine noradrenaline, as the primary transmitter of postganglionic sympathetic neurons, orchestrates motility and secretory reflexes and controls arterial perfusion as ...
Winfried Neuhuber, Jürgen Wörl
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