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The enteric nervous system: the hub in a star network
Nature Reviews Gastroenterology and Hepatology, 2020The enteric nervous system (ENS) is an important component of gastrointestinal function and a pivotal hub connecting the gut to other organs. A new study now explores the human and mouse ENS at the single-cell level, providing key insights into the transcriptomic landscape of the ENS and its constituent cells.
Ana Carina Bon Frauches Oliveira +1 more
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Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2018 The enteric nervous system (ENS) is crucial for essential gastrointestinal physiologic functions such as motility, fluid secretion, and blood flow. The gut is colonized by trillions of bacteria that regulate host production of several signaling molecules
Filipe de Vadder +2 more
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New England Journal of Medicine, 1996
The enteric nervous system is a collection of neurons in the gastrointestinal tract1 that constitutes the “brain of the gut” and can function independently of the central nervous system.2 This system controls the motility,3,4 exocrine and endocrine secretions,5 and microcirculation6 of the gastrointestinal tract; it is also involved in regulating ...
R K, Goyal, I, Hirano
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The enteric nervous system is a collection of neurons in the gastrointestinal tract1 that constitutes the “brain of the gut” and can function independently of the central nervous system.2 This system controls the motility,3,4 exocrine and endocrine secretions,5 and microcirculation6 of the gastrointestinal tract; it is also involved in regulating ...
R K, Goyal, I, Hirano
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Overview of the Enteric Nervous System
Seminars in Neurology, 2023AbstractPropulsion of contents in the gastrointestinal tract requires coordinated functions of the extrinsic nerves to the gut from the brain and spinal cord, as well as the neuromuscular apparatus within the gut. The latter includes excitatory and inhibitory neurons, pacemaker cells such as the interstitial cells of Cajal and fibroblast-like cells ...
Gary M, Mawe +2 more
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Plasticity in the enteric nervous system
Gastroenterology, 1999Enteric ganglia can maintain integrated functions, such as the peristaltic reflex, in the absence of input from the central nervous system, which has a modulatory role. Several clinical and experimental observations suggest that homeostatic control of gut function in a changing environment may be achieved through adaptive changes occurring in the ...
GIARONI, CRISTINA +4 more
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Monoamines in the enteric nervous system
Histochemistry and Cell Biology, 2018Recent advances in neurogastroenterology have extended and refined our knowledge on the roles monoamines play in physiology and pathophysiology of the gastrointestinal tract. The catecholamine noradrenaline, as the primary transmitter of postganglionic sympathetic neurons, orchestrates motility and secretory reflexes and controls arterial perfusion as ...
Winfried Neuhuber, Jürgen Wörl
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The human enteric nervous system
Neurogastroenterology & Motility, 2004AbstractDecades of work in animal models have demonstrated that the enteric nervous system (ENS) plays a key role in controlling gut functions. Recent advances made it possible to extend such studies to the ENS of man in health and even in disease. Such studies have already provided new insights into the pathophysiology of inflammatory and possibly ...
M, Schemann, M, Neunlist
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Current Biology
The enteric nervous system (ENS) is a unique component of the autonomic nervous system found within the wall of the gastrointestinal (GI) tract. What distinguishes the ENS is its size, containing as many neurons as the spinal cord, and its ability to function in the absence of connections to the central nervous system.
David R, Linden, Keith A, Sharkey
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The enteric nervous system (ENS) is a unique component of the autonomic nervous system found within the wall of the gastrointestinal (GI) tract. What distinguishes the ENS is its size, containing as many neurons as the spinal cord, and its ability to function in the absence of connections to the central nervous system.
David R, Linden, Keith A, Sharkey
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Annual Review of Neuroscience, 1981
The enteric nervous system can be defined as the intrinsic innervation of the gastrointestinal tract. It is comprised of two major plexuses of ganglion cells and interconnecting fibers as well:as several subsidiary·groupings of fibers (Schofield 1965, Gabella 197o, Furness & Costa 1980). The two gangli onated plexuses are the submucosal (or Meissner's
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The enteric nervous system can be defined as the intrinsic innervation of the gastrointestinal tract. It is comprised of two major plexuses of ganglion cells and interconnecting fibers as well:as several subsidiary·groupings of fibers (Schofield 1965, Gabella 197o, Furness & Costa 1980). The two gangli onated plexuses are the submucosal (or Meissner's
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Development of the Enteric Nervous System
2008The enteric nervous system (ENS) is the largest and the most complex division of the peripheral nervous system [1]. The ENS contains more neurons than the spinal cord and is capable of mediating reflex activity in the absence of central nervous system.
Udo Rolle, Prem Puri
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