Results 231 to 240 of about 17,304,241 (289)

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

The Placode Lineage Contributes to the Enteric Nervous System: A Caution for Cell Transplantation Therapy for Hirschsprung Disease. [PDF]

Cell Mol Gastroenterol Hepatol
Sato S, Sucov HM, Makita T.
europepmc   +1 more source

Neurochemical Remodelling of the Enteric Nervous System Neurons in the Porcine Jejunum Following Low-Dose Glyphosate Exposure. [PDF]

Int J Mol Sci
Palus K, Karpiesiuk A, Jana B.
europepmc   +1 more source

<i>Sox11</i> genes affect neuronal differentiation in the developing zebrafish enteric nervous system. [PDF]

Proc Natl Acad Sci U S A
Huang Y, Li C, Desingu Rajan AR, Bronner ME.   +3 more
europepmc   +1 more source

Evidence of Altered Enteric Nervous System Structure Associated With Severe Dysmotility in a Patient With Ehlers-Danlos Syndrome. [PDF]

ACG Case Rep J
Oelerich K, Bains K, Minchenberg SB, Deshpande V, Iturrino-Moreda J, Kulkarni S.   +5 more
europepmc   +1 more source

Immunization With Bovine Milk Casein Results in Enteric Nervous System Pathology in a Mouse Model of Neuroinflammation. [PDF]

Neurogastroenterol Motil
Chunder R, Weier A, An Y, Zoons A, Hintze M, Kuerten S.   +5 more
europepmc   +1 more source

Morphological evidence suggestive of a hierarchical mode of glial cell diversification and intrinsic developmental plasticity within the murine enteric nervous system. [PDF]

Front Neurosci
Lefèvre MA, Bourgeois M, Soret R, Pilon N.   +3 more
europepmc   +1 more source

The enteric nervous system and neurogastroenterology

Nature Reviews Gastroenterology and Hepatology, 2012
Neurogastroenterology is defined as neurology of the gastrointestinal tract, liver, gallbladder and pancreas and encompasses control of digestion through the enteric nervous system (ENS), the central nervous system (CNS) and integrative centers in sympathetic ganglia.
Jb Furness
exaly   +4 more sources

Enteric nervous system

Current Opinion in Gastroenterology, 2005
The purpose of this review is to provide a synopsis of how the field of enteric neurobiology has advanced during the past 2 years.With more than 500 studies from which to choose, the authors have focused on several themes that illustrate recent progress.
David, Grundy, Michael, Schemann
core   +7 more sources

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The enteric nervous system

Physiological Reviews, 2023
Of all the organ systems in the body, the gastrointestinal tract is the most complicated in terms of the numbers of structures involved, each with different functions, and the numbers and types of signaling molecules utilized. The digestion of food and absorption of nutrients, electrolytes, and water occurs in a hostile luminal environment that ...
Gary Mawe, Keith Sharkey
exaly   +3 more sources