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The enteric nervous system

Current Biology
The enteric nervous system (ENS) is a unique component of the autonomic nervous system found within the wall of the gastrointestinal (GI) tract. What distinguishes the ENS is its size, containing as many neurons as the spinal cord, and its ability to function in the absence of connections to the central nervous system.
David R, Linden, Keith A, Sharkey
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The Enteric Nervous System

Annual Review of Neuroscience, 1981
The enteric nervous system can be defined as the intrinsic innervation of the gastrointestinal tract. It is comprised of two major plexuses of ganglion cells and interconnecting fibers as well:as several subsidiary·groupings of fibers (Schofield 1965, Gabella 197o, Furness & Costa 1980). The two gangli­ onated plexuses are the submucosal (or Meissner's
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Development of the enteric nervous system

Clinics in Perinatology, 2002
Development of the ENS requires the function of a diverse set of genes encoding transcription factors, signaling molecules, and their receptors. Mutations of these genes result in altered ENS function in animals and humans. In particular, such mutations have been shown to contribute to many cases of Hirschsprung's disease. Elucidation of the mechanisms
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Development of the Enteric Nervous System

2007
The enteric nervous system (ENS) is the largest and the most complex division of the peripheral nervous system [1]. The ENS contains more neurons than the spinal cord and is capable of mediating reflex activity in the absence of central nervous system.
Udo Rolle, Prem Puri
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The human enteric nervous system

Neurogastroenterology & Motility, 2004
AbstractDecades of work in animal models have demonstrated that the enteric nervous system (ENS) plays a key role in controlling gut functions. Recent advances made it possible to extend such studies to the ENS of man in health and even in disease. Such studies have already provided new insights into the pathophysiology of inflammatory and possibly ...
M, Schemann, M, Neunlist
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Inflammatory neuropathies of the enteric nervous system☆

Gastroenterology, 2004
Inflammatory neuropathy of the enteric nervous system is emerging as an important topic in the field of neurogastroenterology. Enteric ganglionitis can be either primary or secondary to a wide array of diseases (i.e., paraneoplastic, infectious, and neurological disorders) and is characterized by a dense infiltrate of inflammatory/immune cells mainly ...
DE GIORGIO, ROBERTO   +8 more
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TYPES OF NERVES IN THE ENTERIC NERVOUS SYSTEM

Neuroscience, 1980
The enteric nervous system is one of the three divisions of the autonomic nervous system, the others being the sympathetic and parasympathetic. In contrast to the other divisions, it can perform many functions independently of the central nervous system.
J B, Furness, M, Costa
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Ageing of the enteric nervous system

Mechanisms of Ageing and Development, 2004
The intrinsic neurones of the enteric nervous system (ENS) play a fundamental role in the regulation of gastrointestinal functions. Although much remains to be learnt about the changes that take place in intestinal nerves during ageing, evidence suggests that selective neurodegeneration may occur in the ageing ENS.
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Neurogenesis in the enteric nervous system.

Archives italiennes de biologie, 2010
The enteric nervous system (ENS) represents the highly organized intrinsic innervation of the gastrointestinal tract and plays a critical role for all stages of postnatal life. Severe disturbances of ENS function can significantly influence life quality or, in severe cases, can have acute life-threatening effects.
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Glutamate in the enteric nervous system

Current Opinion in Pharmacology, 2001
Several lines of evidence indicate a role for glutamate in the regulation of gut motility and secretion; however, the receptor subtypes that mediate the effects of this amino acid are still incompletely understood. There has, however, been recent progress in pharmacological characterization of enteric glutamate receptor subtypes. In the past two years,
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