Results 21 to 30 of about 46,863 (291)

Diabetes and the enteric nervous system [PDF]

Neurogastroenterology & Motility, 2007
Abstract  Diabetes is associated with several changes in gastrointestinal (GI) motility and associated symptoms such as nausea, bloating, abdominal pain, diarrhoea and constipation. The pathogenesis of altered GI functions in diabetes is multifactorial and the role of the enteric nervous system (ENS) in this respect has gained significant importance ...
B, Chandrasekharan, S, Srinivasan
openaire   +2 more sources

Digestive symptoms in daily life of chronic adrenal insufficiency patients are similar to irritable bowel syndrome symptoms

Scientific Reports, 2021
Gastrointestinal symptoms are frequent in acute adrenal insufficiency. Although digestive symptoms can significantly reduce quality of life, they are rarely described in patients with treated chronic adrenal insufficiency (CAI).
L. Quénéhervé, D. Drui, J. Blin, M. Péré, E. Coron, G. Barbara, M. R. Barbaro, B. Cariou, M. Neunlist, D. Masson, K. Bach-Ngohou   +10 more
doaj   +1 more source

PGI2 Inhibits Intestinal Epithelial Permeability and Apoptosis to Alleviate ColitisSummary

Cellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: Inflammatory bowel diseases (IBDs) that encompass both ulcerative colitis and Crohn’s disease are a major public health problem with an etiology that has not been fully elucidated.
Camille Pochard, Jacques Gonzales, Anne Bessard, Maxime M. Mahe, Arnaud Bourreille, Nicolas Cenac, Anne Jarry, Emmanuel Coron, Juliette Podevin, Guillaume Meurette, Michel Neunlist, Malvyne Rolli-Derkinderen   +11 more
doaj   +1 more source

Intestinal Epithelial AMPK Deficiency Causes Delayed Colonic Epithelial Repair in DSS-Induced Colitis

Cells, 2022
Dysfunctions in the intestinal barrier, associated with an altered paracellular pathway, are commonly observed in inflammatory bowel disease (IBD). The AMP-activated protein kinase (AMPK), principally known as a cellular energy sensor, has also been ...
Séverine Olivier, Hanna Diounou, Camille Pochard, Lisa Frechin, Emilie Durieu, Marc Foretz, Michel Neunlist, Malvyne Rolli-Derkinderen, Benoit Viollet   +8 more
doaj   +1 more source

ACETYLCHOLINE AND ITS SYNTHESIZING ENZYME CHOLINE ACETYLTRANSPHERASE IN THE ENTERIC NERVOUS SYSTEM [PDF]

Journal of IMAB, 2022
The enteric nervous system is the largest and most complex division of the peripheral nervous system. Located in the wall of the gastrointestinal tract, it is a regulatory and coordination unit of the nervous system.
Desislava M. Marinova, Miroslav L. Dobrev, Tihomir R. Rashev, Iskren K. Gerasimov, Vladislav Nankov, Stefan V. Trifonov   +5 more
doaj   +1 more source

Analysis of enteric nervous system and intestinal epithelial barrier to predict complications in Hirschsprung’s disease

Scientific Reports, 2020
In Hirschsprung’s disease (HSCR), postoperative course remains unpredictable. Our aim was to define predictive factors of the main postoperative complications: obstructive symptoms (OS) and Hirschsprung-associated enterocolitis (HAEC).
Anne Dariel, Lucie Grynberg, Marie Auger, Chloé Lefèvre, Tony Durand, Philippe Aubert, Catherine Le Berre-Scoul, Aurélien Venara, Etienne Suply, Marc-David Leclair, Philine de Vries, Guillaume Levard, Benoit Parmentier, Guillaume Podevin, Françoise Schmitt, Véronique Couvrat, Sabine Irtan, Erik Hervieux, Thierry Villemagne, Hubert Lardy, Carmen Capito, Cécile Muller, Sabine Sarnacki, Jean-François Mosnier, Louise Galmiche, Pascal Derkinderen, Hélène Boudin, Charlène Brochard, Michel Neunlist   +28 more
doaj   +1 more source

Parkinson mice show functional and molecular changes in the gut long before motoric disease onset

Molecular Neurodegeneration, 2021
Background There is increasing evidence that Parkinson’s disease (PD) might start in the gut, thus involving and compromising also the enteric nervous system (ENS). At the clinical onset of the disease the majority of dopaminergic neurons in the midbrain
Manuela Gries, Anne Christmann, Steven Schulte, Maximilian Weyland, Stephanie Rommel, Monika Martin, Marko Baller, Ralph Röth, Stefanie Schmitteckert, Marcus Unger, Yang Liu, Frederik Sommer, Timo Mühlhaus, Michael Schroda, Jean-Pierre Timmermans, Isabel Pintelon, Gudrun A. Rappold, Markus Britschgi, Hilal Lashuel, Michael D. Menger, Matthias W. Laschke, Beate Niesler, Karl-Herbert Schäfer   +22 more
doaj   +1 more source

Enteric neurospheres are not specific to neural crest cultures: implications for neural stem cell therapies. [PDF]

, 2015
Enteric neural stem cells provide hope of curative treatment for enteric neuropathies. Current protocols for their harvesting from humans focus on the generation of 'neurospheres' from cultures of dissociated gut tissue.
Ellen Binder, Kronfli Rania, Binder Ellen, Julie Cooper (709302), Cooper Julie, Thapar Nikhil, Conor McCann, Cananzi Mara, Cananzi, M, Jean-Marie Delalande (709304), Dipa Natarajan (709301), Conor McCann (709305), Cananzi, M. (Mara), Dipa Natarajan, Delalande Jean-Marie, Binder, E, McCann, C.J. (Conor), Nikhil Thapar, Nikhil Thapar (709307), Mara Cananzi (255527), Burns Alan J., Cooper, J.E. (Julie E.), Thapar, N. (Nikhil), Alan J Burns, Delalande, JM, Natarajan, D, Jean-Marie Delalande, Burns, A.J. (Alan), McCann, C, Rania Kronfli (709303), Delalande, J.-M. (Jean-Marie), McCann Conor, Mara Cananzi, Delalande, J-M, Natarajan, D. (Dipa), Julie Cooper, Burns, AJ, Thapar, N, Binder, E. (Ellen), Ellen Binder (709300), Alan J. Burns (709306), Cooper, J, Natarajan Dipa, Kronfli, R, Kronfli, R. (Rania), Rania Kronfli   +45 more
core   +1 more source

Maternal prebiotic supplementation impacts colitis development in offspring mice

Frontiers in Nutrition, 2023
Background and aimsMaternal diet plays a key role in preventing or contributing to the development of chronic diseases, such as obesity, allergy, and brain disorders.
Amélie Lê, Amandine Selle, Philippe Aubert, Tony Durand, Carole Brosseau, Philippe Bordron, Erwan Delage, Samuel Chaffron, Camille Petitfils, Nicolas Cenac, Michel Neunlist, Marie Bodinier, Malvyne Rolli-Derkinderen   +12 more
doaj   +1 more source

Altered epithelial barrier functions in the colon of patients with spina bifida

Scientific Reports, 2022
Our objectives were to better characterize the colorectal function of patients with Spina Bifida (SB). Patients with SB and healthy volunteers (HVs) completed prospectively a standardized questionnaire, clinical evaluation, rectal barostat, colonoscopy ...
Charlène Brochard, Guillaume Bouguen, Raphael Olivier, Tony Durand, Sébastien Henno, Benoît Peyronnet, Mael Pagenault, Chloé Lefèvre, Gaëlle Boudry, Mikael Croyal, Alain Fautrel, Maxime Esvan, Alain Ropert, Anne Dariel, Laurent Siproudhis, Michel Neunlist   +15 more
doaj   +1 more source