Results 31 to 40 of about 46,863 (291)

Impact of Siponimod on Enteric and Central Nervous System Pathology in Late-Stage Experimental Autoimmune Encephalomyelitis. [PDF]

, 2022
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS). Although immune modulation and suppression are effective during relapsing-remitting MS, secondary progressive MS (SPMS) requires neuroregenerative therapeutic options ...
Bigaud, Marc, Michael Enders, Christopher Kapitza, Marc Bigaud, Kirchner, Philipp, Kuerten, Stefanie, Ekici, Arif, Enders, Michael, Kapitza, Christopher, Philipp Kirchner, Wörl, Jürgen, Stefanie Kuerten, Arif Ekici, Jürgen Wörl, Alicia Weier, Weier, Alicia   +15 more
core   +1 more source

Development, Diversity, and Neurogenic Capacity of Enteric Glia

Frontiers in Cell and Developmental Biology, 2022
Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the “support” cells of the enteric nervous system, studies over the past 20 years have unveiled a vast array of functions carried out by enteric glia.
Werend Boesmans, Werend Boesmans, Amelia Nash, Kinga R. Tasnády, Kinga R. Tasnády, Wendy Yang, Wendy Yang, Lincon A. Stamp, Marlene M. Hao   +8 more
doaj   +1 more source

Enteric synucleinopathy: real entity or only a trendy concept?

Free Neuropathology, 2020
An accumulating body of literature has emerged in the past 25 years to show that Parkinson’s disease (PD) is not only a disorder of the brain but also of the gastrointestinal tract and more generally of the gut-brain axis. Gastrointestinal symptoms occur
Adrien de Guilhem de Lataillade, Thibaud Lebouvier, Wendy Noble, Laurene Leclair-Visonneau, Pascal Derkinderen   +4 more
doaj   +1 more source

Late-Stage Glioma Is Associated with Deleterious Alteration of Gut Bacterial Metabolites in Mice

Metabolites, 2022
Brain-gut axis refers to the bidirectional functional connection between the brain and the gut, which sustains vital functions for vertebrates. This connection also underlies the gastrointestinal (GI) comorbidities associated with brain disorders.
Aglae Herbreteau, Philippe Aubert, Mikaël Croyal, Philippe Naveilhan, Stéphanie Billon-Crossouard, Michel Neunlist, Yves Delneste, Dominique Couez, Laetitia Aymeric   +8 more
doaj   +1 more source

Impact of protein kinase CK2 inhibitors on proliferation and differentiation of neural stem cells

Heliyon, 2017
Background: Protein kinases play central roles in cell and tissue development. Protein kinase CK2, an ubiquitously expressed serine/threonine kinase has severe impacts on embryo- and spermatogenesis.
Melanie Bender, Lisa Schwind, David Grundmann, Monika Martin, Markus Klotz, Claudia Götz, Mathias Montenarh, Karl-Herbert Schäfer   +7 more
doaj   +1 more source

Visualization of the human enteric nervous system by probe confocal laser endomicroscopy: a first real-time observation of Hirschsprung’s disease and allied disorders

BMC Medical Imaging, 2021
Background Our group previously proved that the human enteric nervous system can be visualized with confocal laser endomicroscopy after topical application of cresyl violet using surgically resected intestine specimens.
Atsushi Harada, Naoki Shimojima, Masakuni Kobayashi, Shunsuke Kamba, Seiichi Hirobe, Kazuki Sumiyama   +5 more
doaj   +1 more source

A murine model to study the gut bacteria parameters during complex antibiotics like cefotaxime and ceftriaxone treatment

Computational and Structural Biotechnology Journal, 2021
Background: The globally increasing resistance due to extended-spectrum beta-lactamase producing Enterobacteriaceae is a major concern. The objective of this work was to develop a murine model to study the gut bacteria parameters during complex ...
Matthieu Grégoire, Florian Berteau, Ronan Bellouard, Quentin Lebastard, Philippe Aubert, Jacques Gonzales, François Javaudin, Anne Bessard, Pascale Bemer, Éric Batard, Didier Lepelletier, Michel Neunlist, Emmanuel Montassier, Éric Dailly   +13 more
doaj   +1 more source

The regulation of enteric neuron connectivity by semaphorin 5A is affected by the autism-associated S956G missense mutation

iScience
Summary: The neural network of the enteric nervous system (ENS) underlies gastrointestinal functions. However, the molecular mechanisms involved in enteric neuronal connectivity are poorly characterized. Here, we studied the role of semaphorin 5A (Sema5A)
Morgane E. Le Dréan, Catherine Le Berre-Scoul, Vincent Paillé, Martial Caillaud, Thibauld Oullier, Jacques Gonzales, Philippe Hulin, Michel Neunlist, Sophie Talon, Hélène Boudin   +9 more
doaj   +1 more source

OBESITY AND ENTERIC NERVOUS SYSTEM MODULATION: EVIDENCE FROM PRECLINICAL ANIMAL MODELS

, 2022
Nutrient absorption and energy metabolism are regulated by the enteric nervous system (ENS), which thereby controls the onset of obesity. In addition, the interplay between obesity and cognitive dysfunction via the gut-brain axis has been reported ...
Tayebati SK, Gabrielli MG, Amenta F, Cifani C, Bellitto V, Roy P, Martinelli I, Micioni Di Bonaventura MV   +7 more
core  

Enteric Nervous System Impairment in Gastroschisis [PDF]

European Journal of Pediatric Surgery, 2012
After surgical repair of gastroschisis, most neonates exhibit severe intestinal dysmotility. We hypothesized that impaired development of the enteric nervous system or interstitial cells of Cajal (ICC) network contributes to impaired intestinal motility in gastroschisis.
Auber, Frederic, Danzer, Enrico, Noché-Monnery, Marie-Emmanuelle, Sarnacki, Sabine, Trugnan, Germain, Boudjemaa, Sabah, Audry, Georges   +6 more
openaire   +2 more sources