Results 81 to 90 of about 817,024 (288)

Dedicated macrophages organize and maintain the enteric nervous system

Nature, 2023
M. Viola, Marta Chavero-Pieres, Elodie Modave, Marcello Delfini, N. Stakenborg, Maria Cuende Estévez, Naomi Fabre, Iris Appeltans, Tobie Martens, K. Vandereyken, H. Theobald, J. Van Herck, Philippe Petry, S. Verheijden, Sebastiaan De Schepper, A. Sifrim, Zhaoyuan Liu, F. Ginhoux, M. Azhar, A. Schlitzer, G. Matteoli, Katrin Kierdorf, M. Prinz, P. Vanden Berghe, T. Voet, G. Boeckxstaens   +25 more
semanticscholar   +1 more source

Exploring patients’ profiles associated with the resolution of acute calcium pyrophosphate arthritis treatedwith colchicine and prednisone: post hoc analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Induced pluripotent stem cell-derived enteric neural crest cells repopulate human aganglionic tissue-engineered intestine to form key components of the enteric nervous system

Journal of Tissue Engineering, 2020
Models for enteric neuropathies, in which intestinal nerves are absent or injured, are required to evaluate possible cell therapies. However, existing options, including transgenic mice, are variable and fragile.
David F Chang, Samuel M Zuber, Elizabeth A Gilliam, Laura-Marie A Nucho, Gabriel Levin, Fengnan Wang, Anthony I Squillaro, Sha Huang, Jason R Spence, Tracy C Grikscheit   +9 more
doaj   +1 more source

Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis

Arthritis Care &Research, EarlyView.
Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher, Sam Norton, Joseph L. Taylor, Bina Menon, Tom Esterine, Ruth Williams, Leonie S. Taams, Kirsty Bannister, Bruce W. Kirkham   +8 more
wiley   +1 more source

How leaky is the gut in Parkinson’s disease?

EBioMedicine
Summary: The intestinal epithelial barrier (IEB) plays a critical role in health and disease by regulating the absorption of nutrients, electrolytes and water while preventing gut translocation of pathogens.
Pascal Derkinderen, François Cossais, Kristína Kulcsárová, Matej Škorvánek, Loïc Sellier-Montaigne, Emmanuel Coron, Laurène Leclair-Visonneau, Silvia Cerri, Carolina Pellegrini, Malvyne Rolli-Derkinderen   +9 more
doaj   +1 more source

Association between Discordance of Disease Activity Indices and Quantitative Sensory Testing Measures of Nociplastic Pain in Patients with Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Objective This study investigates the association between discordance in commonly collected clinical indicators of rheumatoid arthritis (RA) disease activity and abnormalities in quantitative sensory testing (QST) observed in individuals with nociplastic pain.
Clarice P. Lin, Burcu Aydemir, Jing Song, Lutfiyya N. Muhammad, Tuhina Neogi, Wendy Marder, Clifton O. Bingham, Marcy B. Bolster, Daniel J. Clauw, Dorothy D. Dunlop, Yvonne C. Lee   +10 more
wiley   +1 more source

Imaging neuron-glia interactions in the enteric nervous system

Frontiers in Cellular Neuroscience, 2013
The enteric nervous system (ENS) is a network of neurons and glia within the wall of the gastrointestinal tract that is able to control many aspects of digestive function independently from the central nervous system.
Werend eBoesmans, Michiel A Martens, Nathalie eWeltens, Marlene M Hao, Jan eTack, Carla eCirillo, Pieter eVanden Berghe   +6 more
doaj   +1 more source

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Microbial metabolites alleviate Aß-induced alterations of intestinal epithelial barrier and enteric nervous system connectivity

Journal of Functional Foods
Amyloid-ß (Aß) induced alterations in gut functions, such as reduced motility and compromised barrier integrity contribute to age-related frailty. Therefore, developing fermentation-based products to prevent age-related gut disorders represents a major ...
Rodrigue Brossaud, Valentine S. Moullé, Marina Giblaine, Sergine Even, Marie-Bernadette Maillard, Séverine Chevalier, Thibauld Oullier, Eric Guédon, Yves Le Loir, Moustapha Cissé, Hélène Falentin, Michel Neunlist   +11 more
doaj   +1 more source

Opportunities and Challenges for Single-Unit Recordings from Enteric Neurons in Awake Animals

Micromachines, 2018
Advanced electrode designs have made single-unit neural recordings commonplace in modern neuroscience research. However, single-unit resolution remains out of reach for the intrinsic neurons of the gastrointestinal system.
Bradley B. Barth, Hsin-I Huang, Gianna E. Hammer, Xiling Shen   +3 more
doaj   +1 more source